Ru Y, Wang B-B, Brendel V
Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011-3260, USA.
Curr Top Microbiol Immunol. 2008;326:1-15. doi: 10.1007/978-3-540-76776-3_1.
The spliceosome is a large nuclear structure consisting of dynamically interacting RNAs and proteins. This chapter briefly reviews some of the known components and their interactions. Large-scale proteomics and gene expression studies may be required to unravel the many intricate mechanisms involved in splice site recognition and selection.
剪接体是一种由动态相互作用的RNA和蛋白质组成的大型核结构。本章简要回顾了一些已知的组成成分及其相互作用。可能需要大规模蛋白质组学和基因表达研究来阐明剪接位点识别和选择中涉及的许多复杂机制。