Landreneau R J, Marshall J B, Johnson J A, Boley T M, Hazelrigg S R, Curtis J J, McClelland R N
Division of Cardiothoracic Surgery, University of Missouri School of Medicine, Columbia.
Ann Thorac Surg. 1991 Aug;52(2):325-6; discussion 327. doi: 10.1016/0003-4975(91)91370-b.
Twenty-seven patients with advanced gastroesophageal reflux disease have been treated with combined transthoracic parietal cell vagotomy and Collis-Nissen fundoplication. Gastric acid analyses (n = 20) obtained preoperatively and 6 months postoperatively demonstrated a significant late reduction in gastric acid output. Twenty-six patients (96%) have experienced relief of gastroesophageal reflux disease at a mean of 13.3 months (range, 6 to 25 months) without postvagotomy symptoms. Transthoracic parietal cell vagotomy may be considered as an adjunct to mechanical surgical control of advanced gastroesophageal reflux disease.
27例晚期胃食管反流病患者接受了经胸壁壁细胞迷走神经切断术与科利斯-尼森胃底折叠术联合治疗。术前及术后6个月进行的胃酸分析（n = 20）显示，术后胃酸分泌量显著减少。26例患者（96%）在平均13.3个月（范围6至25个月）时胃食管反流病症状得到缓解，且无迷走神经切断术后症状。经胸壁壁细胞迷走神经切断术可被视为晚期胃食管反流病机械手术控制的辅助手段。
