Baskin-Bey Edwina S, Nyberg Scott L
Division of Transplantation Surgery, William J. von Liebig Transplant Center, Mayo Clinic, Rochester, MN 55905, USA.
Transplant Rev (Orlando). 2008 Jul;22(3):167-70. doi: 10.1016/j.trre.2008.02.005. Epub 2008 Mar 28.
A new kidney allocation scheme is needed to address the current shortage of deceased donor kidneys for transplantation in the United States. With this goal in mind, we have derived a novel utility-based system to balance supply and demand. Our system uses a North American-based recipient risk score and the deceased donor score to maximize the total number of years of renal allograft function as a means to improve allocation of kidneys from deceased donors. Essentially, donor renal allografts are matched to a wait-listed candidate with similar predicted survival, which poses an ethical issue. However, this novel utility-based system is practical and could improve deceased donor renal allocation by minimizing both waste and need for retransplantation.
需要一种新的肾脏分配方案来解决美国目前用于移植的 deceased donor 肾脏短缺的问题。出于这一目标，我们推导出了一种基于效用的新系统来平衡供需。我们的系统使用基于北美的受者风险评分和 deceased donor 评分，以最大化肾移植功能的总年数，作为改善 deceased donor 肾脏分配的一种手段。从本质上讲，供体肾移植与具有相似预测生存期的等待名单上的候选人相匹配，这带来了一个伦理问题。然而，这种基于效用的新系统是切实可行的，并且可以通过最大限度地减少浪费和再次移植的需求来改善 deceased donor 肾脏的分配。
