Matsunoki Aika, Yoshino Hiroshi, Takayanagi Tomoyasu, Kadoya Shinichi, Kotake Masanori, Ishiguro Kaname, Kurokawa Masaru, Morita Katsuya, Bandou Hiroyuki, Yamada Chiyoko, Yamada Tetsuji
Dept. of General and Gastrointestinal Surgery, Ishikawa Prefectural Central Hospital).
Gan To Kagaku Ryoho. 2008 Jun;35(6):991-3.
Pregnancy-associated breast carcinoma is generally defined as cancer that occurs during pregnancy or within 1 year of delivery, although treatment options are the most complicated when the disease is diagnosed during pregnancy. We report the case of a 30-year-old woman who was diagnosed with breast cancer at her 9th week of pregnancy. The patient initially had mastectomy with axillary lymph node dissection. She began adjuvant therapy with 3 courses of epirubicin/cyclophosphamide at 19 weeks of gestation. After delivery of a healthy child, she received one course of epirubicin/cyclophosphamide and 4 courses of docetaxel. Although the data are limited, pregnant patients with cancer can be treated with systemic chemotherapy with minimal risks to the fetus during the second or third trimester. Management of breast cancer during pregnancy requires an interdisciplinary care team and careful consideration of the patient's stage of disease, the gestational age of the fetus, and the preferences of the patient and her family.
