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[腹膜透析中透析液的生物相容性——局限性与改进的可能性]

[Biocompatibility of dialysis fluid in peritoneal dialysis--limitations and possibilities of improvement].

作者信息

Olszowska Anna, Wańkowicz Zofia

机构信息

Wojskowy Instytut Medyczny w Warszawie, CSK MON, Klinika Chorób Wewnetrznych, Nefrologii i Dializoterapii, Poland.

出版信息

Pol Merkur Lekarski. 2008 Apr;24(142):364-7.

PMID:18634375
Abstract

Standard glucose dialysis solutions are characterised by low biocompatibility because of hyperosmolality, low pH, lactate buffer and presence of glucose degradation products. These factors cause failure of peritoneum as dialysis membrane. In our paper we present problems of biocompatibility of glucose-based solutions as well as possibilities of improvement in this field thanks to application of alternative solutions.

摘要

标准葡萄糖透析液的特点是生物相容性低,原因在于高渗性、低pH值、乳酸缓冲液以及葡萄糖降解产物的存在。这些因素导致腹膜作为透析膜失效。在我们的论文中,我们阐述了基于葡萄糖的溶液的生物相容性问题,以及通过应用替代溶液在该领域实现改进的可能性。

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