[使用硫利达嗪治疗的精神分裂症患者发生尖端扭转型多形性室性心动过速]

[Polymorphic ventricular tachycardia of torsade de pointes type in patient with schizophrenia treated with thioridazine].

作者信息

Sinkiewicz Władysław, Balak Wojciech, Fares Issa, Karasek Danuta, Małyszka Piotr, Papke Magdalena

机构信息

Zakład Klinicznych Podstaw Fizjoterapii Collegium Medicum UMK w Toruniu.

出版信息

Pol Arch Med Wewn. 2006 Dec;116(6):1188-91.

PMID:18634530

Abstract

A case of 82 year-old female with schizophrenia treated with thioridazine with a long QT syndrome and polymorphic ventricular tachycardia of torsade de pointes type was presented. Additional predisposing factor for cardiac arrhythmia was diarrhea with subsequent hypokalemia. Infusion of magnesium sulphate, potassium supplementation and thioridazine discontinuation was effective management of the pathient.

摘要

报告了一例82岁患有精神分裂症的女性患者，使用硫利达嗪治疗后出现长QT综合征和尖端扭转型多形性室性心动过速。心律失常的另一个诱发因素是腹泻伴随后的低钾血症。静脉输注硫酸镁、补钾以及停用硫利达嗪对该患者的治疗有效。