Zhou Hai-Tao, Zhou Zhi-Xiang, Zhang Hai-Zen, Bi Jian-Jun, Zhao Ping
Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Jul;11(4):326-30.
To explore the clinical characteristics, diagnosis and treatment regimens for the primary gastric lymphoma (PGL).
The data of 98 PGL patients treated from January 1994 to December 2006 were collected and analyzed retrospectively.
Abdominal pain was the common symptom of PGL. All the patients were at stage I or stage II, and the preoperative diagnosis rate was 56.5%. The overall 1-, 3- and 5-year survival rates were 95.1%, 86.0% and 73.0% respectively. The 5-year survival rates of stage I and stage II patients were 89.5% and 66.7% respectively, and the difference was significant. The 5-year survival rate of patients received operations was 77.2% and that without operation was 75.0%, the difference was not significant.
The therapy based on chemotherapy is preferred for the treatment of PGL. In the cases of serious gastrointestinal complications, indefinite pathological diagnosis or non-effective chemotherapy, operations should be considered.