Namba J, Murase T, Moritomo H, Denno K, Henmi S, Yoshikawa H
Department of Orthopedic Surgery, Minoh City Hospital, Minoh-City, Osaka, Japan.
Handchir Mikrochir Plast Chir. 2008 Oct;40(5):294-8. doi: 10.1055/s-2007-964879. Epub 2008 Jul 17.
There is little information on solitary tumorous calcification causing carpal tunnel syndrome in the literature. This study describes our experience with surgically treated cases of solitary tumorous calcification causing carpal tunnel syndrome.
Seven patients with symptomatic carpal tunnel syndrome who had tumorous calcification in the carpal tunnel confirmed by radiographical examinations and had then undergone open incisional carpal tunnel release were reviewed. The precise location and the appearance of the calcified mass were confirmed with the preoperative radiographic examinations and the operative records. The additional histology and the composition analysis of the calcified mass were also reviewed in five removed calcifications.
Radiographs of each hand revealed a mass of calcification lying anterior to the capitate bone in the carpal tunnel. Intraoperatively, an oval calcified nodule, measuring 10 x 10 x 10 - 18 mm, was observed overlying the capitate, attached firmly to the palmar radiocarpal extrinsic ligament. A composition with an average of 60 % basic calcium phosphate was revealed by infrared absorption spectrometry. Histological sections showed a calcified deposit surrounded by fibrocartilagenous tissue in three cases.
These facts suggest that the pathogenesis of tumorous calcification causing carpal tunnel syndrome is comparable with that of calcifying tendinitis of the rotator cuff in which a cell-mediated reactive process plays an important role at the tendon insertion.
文献中关于导致腕管综合征的孤立性肿瘤性钙化的信息很少。本研究描述了我们对手术治疗的导致腕管综合征的孤立性肿瘤性钙化病例的经验。
回顾了7例有症状的腕管综合征患者,这些患者经影像学检查证实腕管内有肿瘤性钙化,随后接受了开放性切开腕管松解术。通过术前影像学检查和手术记录确定钙化肿块的精确位置和外观。还对5个切除的钙化灶进行了额外的组织学检查和钙化肿块的成分分析。
每只手的X线片显示腕管内头状骨前方有一个钙化肿块。术中,在头状骨上方观察到一个椭圆形钙化结节,大小为10×10×10 - 18毫米,牢固附着于掌侧桡腕外在韧带。红外吸收光谱法显示平均含60%碱性磷酸钙的成分。组织学切片显示3例钙化沉积物被纤维软骨组织包围。
这些事实表明,导致腕管综合征的肿瘤性钙化的发病机制与肩袖钙化性肌腱炎的发病机制相当,其中细胞介导的反应过程在肌腱附着处起重要作用。