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单心室姑息性动脉调转术:这些患者适合进行Fontan手术吗?

The palliative arterial switch procedure for single ventricles: are these patients suitable Fontan candidates?

作者信息

Ceresnak Scott R, Quaegebeur Jan M, Pass Robert H, Hordof Allan J, Liberman Leonardo

机构信息

Department of Pediatrics, Division of Pediatric Cardiology, Morgan Stanley Children's Hospital, New York, New York 10032, USA.

出版信息

Ann Thorac Surg. 2008 Aug;86(2):583-7. doi: 10.1016/j.athoracsur.2008.04.022.

Abstract

BACKGROUND

The traditional first stage of palliation for functional single-ventricle lesions with transposition of the great vessels and systemic outflow tract obstruction has been either the Norwood or Sano procedure or the Damus-Kaye-Stansel procedure. There is limited literature on the use of an arterial switch procedure as the initial staged palliation for functional single ventricles in this setting. This study is an examination of our institutional experience with performing the palliative switch procedure with examination of suitability for Fontan completion and midterm outcome in these patients.

METHODS

This is a retrospective review of our institutional experience from October 1991 through August 2006 on single-ventricle patients with transposition of the great vessels and systemic outflow tract obstruction who underwent a palliative arterial switch procedure.

RESULTS

Nine patients underwent an initial palliative switch procedure. Six of 9 patients underwent completion of palliation with the Fontan procedure and are alive and well. One patient is well and is awaiting the next stage of palliation (78%). There was 1 early operative death (11%) and 1 late death (11%). There was 1 case of recoarctation (11%).

CONCLUSIONS

The palliative switch procedure appears a reasonable surgical option for patients with functional single-ventricle lesions, transposition of the great vessels, and systemic outflow tract obstruction. Patients who have undergone a palliative switch procedure are suitable candidates for completion of palliation with the Fontan procedure.

摘要

背景

对于合并大动脉转位及体循环流出道梗阻的功能性单心室病变,传统的一期姑息治疗方法为诺伍德手术、桑诺手术或达穆斯-凯-斯坦塞尔手术。关于在此种情况下使用动脉调转术作为功能性单心室的初始分期姑息治疗的文献有限。本研究旨在考察我们机构实施姑息性调转术的经验,评估这些患者接受Fontan手术完成姑息治疗的适宜性及中期结局。

方法

这是一项对我们机构1991年10月至2006年8月期间对合并大动脉转位及体循环流出道梗阻且接受姑息性动脉调转术的单心室患者的经验进行的回顾性研究。

结果

9例患者接受了初始姑息性调转术。9例患者中有6例通过Fontan手术完成了姑息治疗,目前存活且状况良好。1例患者情况良好,正在等待下一阶段的姑息治疗(78%)。有1例早期手术死亡(11%)和1例晚期死亡(11%)。有1例再狭窄病例(11%)。

结论

对于功能性单心室病变、大动脉转位及体循环流出道梗阻的患者,姑息性调转术似乎是一种合理的手术选择。接受姑息性调转术的患者是通过Fontan手术完成姑息治疗的合适人选。

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