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Cell Cycle. 2007 Oct 1;6(19):2371-6. doi: 10.4161/cc.6.19.4759. Epub 2007 Jul 18.
2
Reversal of autoimmune disease in lupus-prone New Zealand black/New Zealand white mice by nonmyeloablative transplantation of purified allogeneic hematopoietic stem cells.通过纯化的同种异体造血干细胞非清髓性移植逆转狼疮易感新西兰黑/新西兰白小鼠的自身免疫性疾病
Blood. 2007 Aug 15;110(4):1370-8. doi: 10.1182/blood-2007-03-081497. Epub 2007 Apr 13.
3
Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands.小鼠发育的克隆分析揭示了卵黄囊血岛的多克隆起源。
Dev Cell. 2006 Oct;11(4):519-33. doi: 10.1016/j.devcel.2006.08.001.
4
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation.JAK2 V617F突变发生于真性红细胞增多症的造血干细胞中,并倾向于向红系分化。
Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6224-9. doi: 10.1073/pnas.0601462103. Epub 2006 Apr 7.
5
Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.纯化后的罕见龛位造血干细胞植入可在不进行宿主预处理的情况下纠正严重的淋巴细胞缺陷。
J Exp Med. 2006 Jan 23;203(1):73-85. doi: 10.1084/jem.20051714. Epub 2005 Dec 27.
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Stem cell research: paths to cancer therapies and regenerative medicine.干细胞研究:通往癌症治疗和再生医学之路
JAMA. 2005 Sep 21;294(11):1359-66. doi: 10.1001/jama.294.11.1359.
7
Differential expression of novel potential regulators in hematopoietic stem cells.造血干细胞中新型潜在调节因子的差异表达。
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E. 唐纳·托马斯讲座:正常与肿瘤干细胞

The E. Donnall Thomas lecture: normal and neoplastic stem cells.

作者信息

Weissman Irving L

机构信息

Stanford University School of Medicine, Stanford, California 94305, USA.

出版信息

Biol Blood Marrow Transplant. 2008 Aug;14(8):849-58. doi: 10.1016/j.bbmt.2008.05.003.

DOI:10.1016/j.bbmt.2008.05.003
PMID:18640567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2821216/
Abstract

Dr. Irving Weissman was the honored E. Donnall Thomas lecturer at the Tandem BMT Meetings, held on February 10, 2007, at Keystone, Colorado. Dr. Weissman has been a major player, and has provided us with enormous insight into many areas of biology, dating back to his high school days in Montana. He led an enormously productive career at Stanford University where he has taught us many lessons involving our understanding of lymphocyte homing, stem cell biology, both of the hematopoietic system and other types of stem cells, and also now, about cancer stem cells. Dr. Weissman has made enormous contributions to this burgeoning field that has provided us new insights and new opportunities for treatment strategies. In addition to a very productive laboratory career, he is also currently the director of both the Stem Cell Institute, as well as the Cancer Center at Stanford University. The following text is a modified transcribed version of the presentation made by Dr. Weissman.

摘要

欧文·魏斯曼博士是2007年2月10日在科罗拉多州基斯通举行的串联骨髓移植会议上备受赞誉的E. 唐纳尔·托马斯讲座主讲人。魏斯曼博士一直是一位重要人物,从他在蒙大拿州上高中时起,就为我们提供了许多生物学领域的深刻见解。他在斯坦福大学拥有极其丰硕的职业生涯,在那里他给我们传授了许多经验教训,涉及我们对淋巴细胞归巢、干细胞生物学的理解,包括造血系统和其他类型干细胞的干细胞生物学,以及现在关于癌症干细胞的知识。魏斯曼博士为这个蓬勃发展的领域做出了巨大贡献,该领域为我们提供了新的见解和治疗策略的新机会。除了非常富有成果的实验室工作生涯外,他目前还是干细胞研究所所长以及斯坦福大学癌症中心主任。以下文本是魏斯曼博士演讲的修改转录版本。