Barandon Laurent, Richebé Philippe, Munos Emmanuel, Calderon Joachim, Lafitte Marianne, Lafitte Stéphane, Couffinhal Thierry, Roques Xavier
Department of Cardiac Surgery and Anesthesiology, Hôpital Cardiologique du Haut-Levêque, 33600 Pessac, France.
Interact Cardiovasc Thorac Surg. 2008 Oct;7(5):789-93. doi: 10.1510/icvts.2008.183665. Epub 2008 Jul 18.
Left ventricle dysfunction and comorbidities are responsible for a large number of complications after CABG. OPCAB could be an interesting alternative for very high-risk patients. Patients were included if EuroSCORE >9, or with at least two of the following criteria, severe LV dysfunction, recent myocardial infarction (MI), terminal renal failure, lung dysfunction, PVD, BMI>30. Patients were operated using the Octopus (Medtronic) system. One hundred and twenty patients, mean age 68+/-10 years, 72% male, were operated. Mean EuroSCORE was 10.2+/-5.3, LV function 36.79+/-11.3%, recent MI 57%, renal failure 52%, COPD 44%, PVD 52%, obesity 34%. Mean graft per patient was 2.1+/-0.8. Three patients underwent secondary PTCA treatment for incomplete revascularization. Combined surgery was required for 20%. Early mortality was 3%. Intensive care unit stay was 2.7 days. Early complications were: low output syndrome 3%, MI 0.8%, stroke 0.8%, kidney support 7%. Graft patency was systematically analyzed with MCTA or angiocardiography. OPCAB strategy seems to be safe and secure in this population of very high-risk patients reducing multi-organ failure. However, long-term results are needed to confirm this strategy.
左心室功能障碍和合并症是冠状动脉旁路移植术(CABG)后大量并发症的原因。对于极高风险患者,非体外循环冠状动脉旁路移植术(OPCAB)可能是一种有趣的替代方法。如果欧洲心脏手术风险评估系统(EuroSCORE)>9,或符合以下至少两项标准,即严重左心室功能障碍、近期心肌梗死(MI)、终末期肾衰竭、肺功能障碍、外周血管疾病(PVD)、体重指数(BMI)>30,则纳入患者。患者使用章鱼(美敦力)系统进行手术。120例患者接受了手术,平均年龄68±10岁,72%为男性。平均EuroSCORE为10.2±5.3,左心室功能为36.79±11.3%,近期心肌梗死占57%,肾衰竭占52%,慢性阻塞性肺疾病(COPD)占44%,外周血管疾病占52%,肥胖占34%。每位患者平均移植血管数为2.1±0.8。3例患者因血管再通不完全接受了二次经皮冠状动脉腔内血管成形术(PTCA)治疗。20%的患者需要联合手术。早期死亡率为3%。重症监护病房停留时间为2.7天。早期并发症包括:低心排血量综合征3%,心肌梗死0.8%,中风0.8%,肾脏支持治疗7%。使用多层螺旋CT血管造影(MCTA)或心血管造影对移植血管通畅情况进行系统分析。在这群极高风险患者中,OPCAB策略似乎安全可靠,可减少多器官功能衰竭。然而,需要长期结果来证实这一策略。