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极高危患者的非体外循环冠状动脉搭桥手术:调整及初步结果

Off-pump coronary artery bypass surgery in very high-risk patients: adjustment and preliminary results.

作者信息

Barandon Laurent, Richebé Philippe, Munos Emmanuel, Calderon Joachim, Lafitte Marianne, Lafitte Stéphane, Couffinhal Thierry, Roques Xavier

机构信息

Department of Cardiac Surgery and Anesthesiology, Hôpital Cardiologique du Haut-Levêque, 33600 Pessac, France.

出版信息

Interact Cardiovasc Thorac Surg. 2008 Oct;7(5):789-93. doi: 10.1510/icvts.2008.183665. Epub 2008 Jul 18.

Abstract

Left ventricle dysfunction and comorbidities are responsible for a large number of complications after CABG. OPCAB could be an interesting alternative for very high-risk patients. Patients were included if EuroSCORE >9, or with at least two of the following criteria, severe LV dysfunction, recent myocardial infarction (MI), terminal renal failure, lung dysfunction, PVD, BMI>30. Patients were operated using the Octopus (Medtronic) system. One hundred and twenty patients, mean age 68+/-10 years, 72% male, were operated. Mean EuroSCORE was 10.2+/-5.3, LV function 36.79+/-11.3%, recent MI 57%, renal failure 52%, COPD 44%, PVD 52%, obesity 34%. Mean graft per patient was 2.1+/-0.8. Three patients underwent secondary PTCA treatment for incomplete revascularization. Combined surgery was required for 20%. Early mortality was 3%. Intensive care unit stay was 2.7 days. Early complications were: low output syndrome 3%, MI 0.8%, stroke 0.8%, kidney support 7%. Graft patency was systematically analyzed with MCTA or angiocardiography. OPCAB strategy seems to be safe and secure in this population of very high-risk patients reducing multi-organ failure. However, long-term results are needed to confirm this strategy.

摘要

左心室功能障碍和合并症是冠状动脉旁路移植术(CABG)后大量并发症的原因。对于极高风险患者,非体外循环冠状动脉旁路移植术(OPCAB)可能是一种有趣的替代方法。如果欧洲心脏手术风险评估系统(EuroSCORE)>9,或符合以下至少两项标准,即严重左心室功能障碍、近期心肌梗死(MI)、终末期肾衰竭、肺功能障碍、外周血管疾病(PVD)、体重指数(BMI)>30,则纳入患者。患者使用章鱼(美敦力)系统进行手术。120例患者接受了手术,平均年龄68±10岁,72%为男性。平均EuroSCORE为10.2±5.3,左心室功能为36.79±11.3%,近期心肌梗死占57%,肾衰竭占52%,慢性阻塞性肺疾病(COPD)占44%,外周血管疾病占52%,肥胖占34%。每位患者平均移植血管数为2.1±0.8。3例患者因血管再通不完全接受了二次经皮冠状动脉腔内血管成形术(PTCA)治疗。20%的患者需要联合手术。早期死亡率为3%。重症监护病房停留时间为2.7天。早期并发症包括:低心排血量综合征3%,心肌梗死0.8%,中风0.8%,肾脏支持治疗7%。使用多层螺旋CT血管造影(MCTA)或心血管造影对移植血管通畅情况进行系统分析。在这群极高风险患者中,OPCAB策略似乎安全可靠,可减少多器官功能衰竭。然而,需要长期结果来证实这一策略。

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