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饮食摄入模式可能解释了伊朗女性心血管危险因素的高患病率。

Food intake patterns may explain the high prevalence of cardiovascular risk factors among Iranian women.

作者信息

Esmaillzadeh Ahmad, Azadbakht Leila

机构信息

Department of Nutrition, School of Public Health, and Food Security and Nutrition Research Center, Isfahan University of Medical Sciences, Isfahan PO Box 81745, Iran.

出版信息

J Nutr. 2008 Aug;138(8):1469-75. doi: 10.1093/jn/138.8.1469.

Abstract

Some cardiovascular risk factors are more prevalent in Middle Eastern countries than in other parts of the world. Lifestyle-related factors, including diet, might account for this discrepancy. We aimed to identify the association between food intake patterns and cardiovascular risk factors among Iranian adult women. We studied 486 apparently healthy Iranian women aged 40-60 y. We used a Willett-format FFQ for collecting dietary data. Fasting plasma glucose (FPG) concentrations, lipid profiles, and blood pressure were measured. Diabetes was defined as FPG > or = 6.93 mmol/L; dyslipidemia was based on Adult Treatment Panel III and hypertension on Joint National Committee VI recommendations. The presence of at least 1 risk factor and at least 2 risk factors of the 3 major risk factors for cardiovascular disease (hypertension, dyslipidemia, and diabetes) was also evaluated. We identified 3 major eating patterns (healthy, Western, and Iranian). After controlling for potential confounders, subjects in the top quintile of the healthy dietary pattern were less likely to have dyslipidemia [odds ratio (OR), 0.36; 95% CI, 0.19-0.53], hypertension (OR, 0.33; 95% CI, 0.17-0.60), at least 1 (OR, 0.30; 95% CI, 0.18-0.58), and at least 2 risk factors (OR, 0.39; 95% CI, 0.20-0.77) compared with the lowest quintile. In contrast, those with greater adherence to the Western dietary pattern had greater odds for cardiovascular risk factors (OR, 2.59-3.11; P < 0.05). The Iranian dietary pattern was significantly associated with dyslipidemia (OR, 1.73; 95% CI, 1.02-2.99) and at least 1 risk factor (OR, 1.89; 95% CI, 1.05-3.20). The major dietary patterns and diabetes were not associated. Eating patterns of this Middle Eastern population might explain the higher prevalence of some cardiovascular risk factors in this region. However, our findings need to be confirmed in other Middle Eastern countries.

摘要

一些心血管危险因素在中东国家比在世界其他地区更为普遍。包括饮食在内的与生活方式相关的因素可能是造成这种差异的原因。我们旨在确定伊朗成年女性的食物摄入模式与心血管危险因素之间的关联。我们研究了486名年龄在40至60岁之间、外表健康的伊朗女性。我们使用威尔特格式的食物频率问卷来收集饮食数据。测量空腹血糖(FPG)浓度、血脂谱和血压。糖尿病定义为FPG≥6.93 mmol/L;血脂异常根据成人治疗小组III的标准判定,高血压根据美国国家联合委员会VI的建议判定。我们还评估了心血管疾病三大危险因素(高血压、血脂异常和糖尿病)中至少存在1种危险因素以及至少存在2种危险因素的情况。我们确定了三种主要的饮食模式(健康型、西方型和伊朗型)。在控制了潜在混杂因素后,与最低五分位数相比,处于健康饮食模式最高五分位数的受试者患血脂异常的可能性较小[比值比(OR),0.36;95%置信区间(CI),0.19 - 0.53],患高血压的可能性较小(OR,0.33;95% CI,0.17 - 0.60),存在至少1种危险因素的可能性较小(OR,0.30;95% CI,0.18 - 0.58),以及存在至少2种危险因素的可能性较小(OR,0.39;95% CI,0.20 - 0.77)。相比之下,那些更坚持西方饮食模式的人患心血管危险因素的几率更高(OR,2.59 - 3.11;P < 0.05)。伊朗饮食模式与血脂异常(OR,1.73;95% CI,1.02 - 2.99)和至少1种危险因素(OR,1.89;95% CI,1.05 - 3.20)显著相关。主要饮食模式与糖尿病无关联。该中东人群的饮食模式可能解释了该地区某些心血管危险因素的较高患病率。然而,我们的研究结果需要在其他中东国家得到证实。

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