Tracy Kelly A, Quillin John M, Wilson Diane Baer, Borzelleca Joseph, Jones Resa M, McClish Donna, Bowen Deborah, Bodurtha Joann
Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA.
Genet Med. 2008 Aug;10(8):621-5. doi: 10.1097/gim.0b013e31817c0355.
To summarize the impact of a family history of breast cancer on mammography practices and beliefs.
Survey data concerning breast health practices and beliefs were utilized for a cross-sectional analysis. Participants were 899 racially diverse nonpregnant women 40 years and older without breast cancer. The impact of various aspects of cancer family history on mammography, perceived barriers to and benefits of screening, and perceived breast cancer risk was assessed.
More women with a first-degree relative with breast cancer reported a mammogram within the past year and rated their breast cancer risk higher. Death of a first-degree relative impacted the belief that breast cancer can be cured with early detection. Degree of relatedness of affected relative impacted mammography practice and risk perceptions.
Family history of breast cancer impacted mammography adherence, beliefs about outcomes with early detection, and risk perceptions. Breast cancer death in a family may be a better predictor of beliefs about breast cancer detection and cure than family history of cancer alone. These findings have implications for how screening recommendations and risk information are communicated to patients with different familial cancer experiences.
总结乳腺癌家族史对乳房X光检查实践及观念的影响。
利用有关乳房健康实践及观念的调查数据进行横断面分析。参与者为899名年龄在40岁及以上、未患乳腺癌、种族各异的非孕妇女性。评估癌症家族史的各个方面对乳房X光检查、筛查的感知障碍及益处,以及感知到的乳腺癌风险的影响。
更多有乳腺癌一级亲属的女性报告在过去一年内进行过乳房X光检查,并认为自己患乳腺癌的风险更高。一级亲属的死亡影响了乳腺癌可通过早期检测治愈的观念。受影响亲属的亲缘程度影响乳房X光检查实践及风险认知。
乳腺癌家族史影响乳房X光检查的依从性、对早期检测结果的观念以及风险认知。家族中的乳腺癌死亡可能比单纯的癌症家族史更能预测对乳腺癌检测及治愈的观念。这些发现对如何向有不同家族癌症经历的患者传达筛查建议及风险信息具有启示意义。