Goulart Dario Grechi, Sano Ronaldo Yuti, Cursino Sylvia Regina Temer, Takahashi Walter Yukihiko
Departamento de Oftalmologia, Santa Casa de São PauloSão Paulo, SP, Brasil.
Arq Bras Oftalmol. 2008 May-Jun;71(3):342-7. doi: 10.1590/s0004-27492008000300007.
Retinal photocoagulation under poor visualization condition is often required. Transscleral infrared laser can be used as an alternative to regular transpupillary treatment. Based upon retinographic measurements, we proposed to estimate the reproducibility as well as ocular wall permeability rate for this treatment. Our primary goal was to evaluate whether this technique can deliver adequate photocoagulation at predetermined parameters without direct retinal visualization.
In New Zealand pigmented rabbits, optimal transscleral infrared diode laser settings were administered to the right eye. With the same parameters, transpupillary photocoagulation was repeated in the left eye. Retinographic and clinical examinations were performed immediately and two months later.
Ocular wall permeability rate varied between 58.95 and 63.87%. Average permeability using a power of 300 mW (63.14%) was found to be higher than that encountered before its enhancement up to 500 mW (59.11%), (P<0.05).
Setting parameters showed dose-response effect. No retinal hole or retinal detachment was noticed in any rabbit. Transscleral infrared photocoagulation appeared to be a reproducible and secure method in the experimental model.
在可视化条件不佳的情况下,常常需要进行视网膜光凝。巩膜外红外激光可作为常规经瞳孔治疗的替代方法。基于视网膜成像测量,我们提议评估这种治疗方法的可重复性以及眼壁渗透率。我们的主要目标是评估该技术在不直接观察视网膜的情况下,能否在预定参数下实现充分的光凝。
对新西兰有色家兔的右眼给予最佳巩膜外红外二极管激光设置。以相同参数对左眼进行经瞳孔光凝。立即以及两个月后进行视网膜成像和临床检查。
眼壁渗透率在58.95%至63.87%之间变化。发现使用300 mW功率时的平均渗透率(63.14%)高于功率增强至500 mW之前的平均渗透率(59.11%),(P<0.05)。
设置参数显示出剂量反应效应。在任何家兔中均未发现视网膜裂孔或视网膜脱离。在实验模型中,巩膜外红外光凝似乎是一种可重复且安全的方法。