经巩膜视网膜冷冻术、透热疗法和二极管激光光凝术后巩膜抗张强度的比较。
Comparison of scleral tensile strength after transscleral retinal cryopexy, diathermy, and diode laser photocoagulation.
作者信息
Han D P, Nash R W, Blair J R, O'Brien W J, Medina R R
机构信息
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, USA.
出版信息
Arch Ophthalmol. 1995 Sep;113(9):1195-9. doi: 10.1001/archopht.1995.01100090121033.
OBJECTIVES
To determine the effect of transscleral diode photocoagulation on the tensile strength of sclera in an experimental rabbit model and to compare it with that of transscleral cryotherapy and diathermy.
METHODS
Twenty-four Dutch-belted rabbits received one of the following three treatment modalities in one eye: (1) transscleral cryotherapy, (2) transscleral diathermy, or (3) transscleral diode laser photocoagulation. The opposite eye served as a paired control. Tensile strength measurements of scleral strips excised from areas of treatment were obtained 6 weeks later.
RESULTS
No statistically significant difference in mean tensile strength was observed between eyes receiving transscleral cryopexy (n = 7) or transscleral diode photocoagulation (n = 8) and their corresponding, paired, control eyes. In contrast, transscleral diathermy reduced mean scleral tensile strength to 26% of that of the paired control eyes (n = 8, P = .0001).
CONCLUSIONS
In this rabbit model, scleral weakening is significant following transscleral diathermy while transscleral cryopexy or transscleral diode photocoagulation produces no significant weakening relative to paired, untreated controls.
目的
在实验性兔模型中确定经巩膜二极管光凝对巩膜抗张强度的影响，并将其与经巩膜冷冻疗法和透热疗法进行比较。
方法
24只荷兰带兔的一只眼睛接受以下三种治疗方式之一：（1）经巩膜冷冻疗法，（2）经巩膜透热疗法，或（3）经巩膜二极管激光光凝。对侧眼作为配对对照。6周后，对从治疗区域切除的巩膜条进行抗张强度测量。
结果
接受经巩膜冷冻治疗（n = 7）或经巩膜二极管光凝（n = 8）的眼睛与其相应的配对对照眼之间，平均抗张强度未观察到统计学上的显著差异。相比之下，经巩膜透热疗法使巩膜平均抗张强度降至配对对照眼的26%（n = 8，P = .0001）。
结论
在该兔模型中，经巩膜透热疗法后巩膜明显变薄，而经巩膜冷冻疗法或经巩膜二极管光凝相对于配对的未治疗对照眼未产生明显变薄。
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