Ng E Y K, Sree S Vinitha, Ng K H, Kaw G
Office of Biomedical Research, National University Hospital, Singapore.
Technol Cancer Res Treat. 2008 Aug;7(4):295-308. doi: 10.1177/153303460800700404.
Breast cancer is the most frequently occurring malignancy in women. It is characterized by a high mortality rate. For the purpose of detecting this life threatening disease, research efforts are being made worldwide to exploit new technologies, to improve the detection accuracy of current devices and to develop new detection devices, comprehensive diagnostic procedures, and protocols. One such technology that is gaining popular attention over the recent years is the usage of electrical characteristics of the breast tissue to differentiate normal and cancerous tissues. Most of the devices using this technology are currently being used as adjunct diagnostic tools to improve the detection accuracy of established techniques like mammography and ultrasound. Also, early detection of breast cancer can help save many thousands of lives every year and can also reduce unnecessary healthcare expenditure caused by advanced stage treatment options. Hence, more research is also being done to adapt these devices into screening tools for early detection of breast cancer. The main objective of this review is to highlight the features of the currently available commercial devices that use this technology for breast cancer detection. The electrical behavior of normal and cancerous breast tissues is first presented. The various commercial devices that utilize electrical impedance or electropotentials for breast cancer detection are then described. Finally, conclusions and potential areas of research are highlighted.
乳腺癌是女性中最常见的恶性肿瘤。其特点是死亡率高。为了检测这种危及生命的疾病,世界各地都在努力开发新技术,提高现有设备的检测准确性,并开发新的检测设备、综合诊断程序和方案。近年来受到广泛关注的一种技术是利用乳腺组织的电学特性来区分正常组织和癌组织。目前,大多数使用该技术的设备都被用作辅助诊断工具,以提高乳腺X线摄影和超声等现有技术的检测准确性。此外,早期发现乳腺癌每年可挽救成千上万人的生命,还可减少晚期治疗方案导致的不必要医疗支出。因此,人们也在进行更多研究,将这些设备应用于乳腺癌早期检测的筛查工具。本综述的主要目的是突出目前使用该技术进行乳腺癌检测的商用设备的特点。首先介绍正常和癌性乳腺组织的电学行为。然后描述利用电阻抗或电势进行乳腺癌检测的各种商用设备。最后,强调结论和潜在的研究领域。