细针穿刺活检作为口腔内小涎腺腺样囊性癌的辅助诊断工具。
Fine-needle aspiration biopsy as an auxiliary diagnostic tool on intraoral minor salivary gland adenoid cystic carcinoma.
作者信息
Netto Juliana de Noronha Santos, Miranda Aguida Maria Menezes Aguiar, da Silveira Henrique Martins, dos Santos Teresa Cristina Ribeiro Bartholomeu, Pires Fábio Ramôa
机构信息
Estacio de Sa University, Rio de Janeiro, Brazil.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Aug;106(2):242-5. doi: 10.1016/j.tripleo.2008.04.015.
BACKGROUND
Fine-needle aspiration biopsy (FNAB) is useful in diagnosis of major salivary gland adenoid cystic carcinoma (ACC), but it has been rarely reported on minor salivary gland ACC.
OBJECTIVE
The aim of this study was to report the utility of FNAB on diagnosis of ACC involving minor salivary glands.
STUDY DESIGN
Three patients presenting ACC involving the palate (2 cases) and buccal mucosa (1 case), with a mean age of 36 years and 2:1 female-to-male ratio, were included in the study. All of the patients were submitted to FNAB for diagnostic purposes.
RESULTS
All smears were stained with hematoxylin-eosin, Papanicolaou, and Diff-Quik and showed the presence of small polyhedral cells with hyperchromatic nuclei and extracellular basophilic globular amorphous substance, compatible with ACC. Diagnosis of the 3 cases was subsequently confirmed through histopathology.
CONCLUSION
The FNAB was easy to perform and cost-effective, and proved to be an useful adjunctive tool in diagnosis of intraoral ACC.
背景
细针穿刺活检（FNAB）有助于诊断大唾液腺腺样囊性癌（ACC），但关于小唾液腺ACC的报道较少。
目的
本研究旨在报告FNAB在诊断累及小唾液腺的ACC中的应用价值。
研究设计
纳入3例累及腭部（2例）和颊黏膜（1例）的ACC患者，平均年龄36岁，男女比例为2:1。所有患者均接受FNAB以明确诊断。
结果
所有涂片均用苏木精-伊红、巴氏和Diff-Quik染色，显示存在小的多面体细胞，核染色质增多，并有细胞外嗜碱性球状无定形物质，符合ACC表现。随后通过组织病理学证实了3例患者的诊断。
结论
FNAB操作简便、成本效益高，被证明是诊断口腔内ACC的有用辅助工具。
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