一种DNA等轴对称植物病毒的球平均结构：花椰菜花叶病毒。

The spherically averaged structure of a DNA isometric plant virus: cauliflower mosaic virus.

作者信息

Kruse J, Timmins P, Witz J

机构信息

Département de Virologie, Institut de Biologie Moléculaire et Cellulaire de CNRS, 15 rue Descartes, 6700 Strasbourg, France.

出版信息

Virology. 1987 Jul;159(1):166-8. doi: 10.1016/0042-6822(87)90361-8.

DOI:10.1016/0042-6822(87)90361-8

PMID:18644567

Abstract

The organization of cauliflower mosaic virus was reinvestigated by neutron small-angle scattering in buffers containing various amounts of D2O. The molecular weight of the virions and their DNA content were determined and found to agree well with the known primary structure of the nucleic acid. The capsid probably possesses a T = 7 icosahedral organization. The exceptionally low packing density of the outer protein shell may account for some of the unusual properties of these very stable virions.

摘要

通过在含有不同量重水的缓冲液中进行中子小角散射，对花椰菜花叶病毒的结构进行了重新研究。测定了病毒粒子的分子量及其DNA含量，发现与已知的核酸一级结构非常吻合。衣壳可能具有T = 7的二十面体结构。外层蛋白质壳极低的堆积密度可能解释了这些非常稳定的病毒粒子的一些异常特性。