Ike S O
Cardiology Unit, Department of Medicine, University Of Nigeria Teaching Hospital (UNTH), PMB 01129, Enugu 400001, Nigeria.
Trans R Soc Trop Med Hyg. 2008 Dec;102(12):1214-8. doi: 10.1016/j.trstmh.2008.06.008. Epub 2008 Jul 21.
This was a hospital-based study designed to determine the prevalence and pattern of valvular heart diseases (VHD) seen at the echocardiographic laboratory of the University of Nigeria Teaching Hospital, Enugu, Nigeria. It was also aimed at evaluating the age and gender distribution, as well as the aetiological diagnosis, of these disease presentations. All the 2527 patients referred for echocardiography over the 10 year period from February 1991 to January 2001 were consecutively studied. VHDs were diagnosed in 957 (38%) of the patients. There were 529 males and 428 females, with an age range of 6 months to 89 years. One hundred and forty-eight (16%) of them presented in the first two decades of life. Mitral valve diseases accounted for 654 (68%), aortic valve diseases 233 (25%), tricuspid valve diseases 51 (5%) and pulmonary valve diseases 19 (2%) of the cases. All four valves were involved in 15 (2%) patients. Rheumatic aetiology was the most common presumptive diagnosis, with 568 (59%) patients. The frequency pattern of VHDs in this study was high. This poses a number of challenges, one of which is the need for availability of interventions, such as non-invasive and minimally invasive surgeries.
这是一项基于医院的研究,旨在确定在尼日利亚埃努古的尼日利亚大学教学医院超声心动图实验室所见到的心脏瓣膜疾病(VHD)的患病率和模式。该研究还旨在评估这些疾病表现的年龄和性别分布以及病因诊断。对1991年2月至2001年1月这10年期间转诊进行超声心动图检查的所有2527例患者进行了连续研究。957例(38%)患者被诊断为心脏瓣膜疾病。其中男性529例,女性428例,年龄范围为6个月至89岁。其中148例(16%)在生命的前二十年出现。二尖瓣疾病占病例的654例(68%),主动脉瓣疾病233例(25%),三尖瓣疾病51例(5%),肺动脉瓣疾病19例(2%)。15例(2%)患者四个瓣膜均受累。风湿性病因是最常见的推测诊断,有568例(59%)患者。本研究中心脏瓣膜疾病的发病频率模式较高。这带来了许多挑战,其中之一是需要有干预措施,如非侵入性和微创外科手术。