Suppr超能文献

尼日利亚西南部风湿性心脏病的新面貌。

The new face of rheumatic heart disease in South West Nigeria.

机构信息

Department of Medicine, College of Health Sciences, Osun State University, Osogbo, Osun State, Nigeria ; Department of Medicine, LAUTECH Teaching Hospital, Osogbo, Osun State, Nigeria.

出版信息

Int J Gen Med. 2013 May 23;6:375-81. doi: 10.2147/IJGM.S44289. Print 2013.

Abstract

PURPOSE

To determine the current prevalence of rheumatic heart disease (RHD), clinical features, types of valvular lesions, complications and mortality, at Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Osogbo, South West Nigeria.

METHODS

We conducted a retrospective, descriptive study of all the cases of RHD seen in the medical outpatient clinics and wards of LAUTECH for 9 years, from January 2003 to December 2011. Statistical analysis of data obtained was done using SPSS 16.

RESULTS

The total number of attendees of all the medical outpatient clinics during the 9-year period was 67,378, with a subset of 9423 attending the cardiology clinic. There were 11 cases of RHD, which translates to a prevalence of 0.16/1000 and 1.2/1000 for medical outpatient clinics and the cardiology clinic respectively. The mean age of the patients was 25.64 ± 9.65 years, age range 14-40 years and male to female ratio of 1:1.2. The most common valve affected was mitral (90.9%), followed by the aortic (36.4%), and the tricuspid (18.2%). Mitral and aortic lesions coexisted in 18.2% of the patients, and late presentation was common in all RHD cases. Heart failure was the most common complication (90.9%). Other complications were secondary pulmonary hypertension (36.4%), infective endocarditis (27.3%), atrial fibrillation (27.3%), cardioembolic cerebrovascular disease (18.2%), and atrial flutter (9.1%). Mortality was 9.1%, while only one patient (9.1%) had definitive surgery. Financial constraints precluded others from having definitive surgery.

CONCLUSION

The prevalence of RHD has declined considerably as a result of improvements in the primary health care delivery system, with widespread use of appropriate antibiotic therapy for sore throats resulting in the prevention of rheumatic fever and RHD. However, late presentation is still very common, hence we advocate a more aggressive drive to make the Drakensberg declaration on the control of rheumatic fever and rheumatic heart disease functional in our practice area.

摘要

目的

在尼日利亚西南部奥索戈博的拉多克·奥廷加大学教学医院(LAUTECH),确定风湿性心脏病(RHD)的当前流行率、临床特征、瓣膜病变类型、并发症和死亡率。

方法

我们对 2003 年 1 月至 2011 年 12 月期间在 LAUTECH 内科门诊和病房就诊的所有 RHD 病例进行了回顾性描述性研究。使用 SPSS 16 对获得的数据进行统计分析。

结果

9 年间,所有内科门诊就诊者总数为 67378 人,其中有 9423 人就诊于心脏病学门诊。共有 11 例 RHD,患病率分别为 0.16/1000 和 1.2/1000,用于内科门诊和心脏病学门诊。患者的平均年龄为 25.64 ± 9.65 岁,年龄范围为 14-40 岁,男女比例为 1:1.2。受影响最常见的瓣膜是二尖瓣(90.9%),其次是主动脉瓣(36.4%)和三尖瓣(18.2%)。18.2%的患者同时存在二尖瓣和主动脉瓣病变,所有 RHD 病例均表现为晚期。心力衰竭是最常见的并发症(90.9%)。其他并发症包括继发性肺动脉高压(36.4%)、感染性心内膜炎(27.3%)、心房颤动(27.3%)、心脑栓塞性脑血管病(18.2%)和心房扑动(9.1%)。死亡率为 9.1%,仅有 1 例患者(9.1%)接受了确定性手术。由于经济限制,其他人无法接受确定性手术。

结论

由于初级卫生保健提供系统的改善,广泛使用适当的抗生素治疗咽痛,从而预防风湿热和 RHD,RHD 的患病率已大幅下降。然而,晚期表现仍然非常普遍,因此我们主张更积极地推动我们实践领域的德拉肯斯堡宣言,以实现风湿热和风湿性心脏病的控制。

相似文献

引用本文的文献

3
Cardiovascular disease in Africa: epidemiological profile and challenges.非洲的心血管疾病:流行病学特征及挑战。
Nat Rev Cardiol. 2017 May;14(5):273-293. doi: 10.1038/nrcardio.2017.19. Epub 2017 Feb 23.

本文引用的文献

1
Echocardiography screening for rheumatic heart disease in Ugandan schoolchildren.超声心动图筛查乌干达学童风湿性心脏病。
Circulation. 2012 Jun 26;125(25):3127-32. doi: 10.1161/CIRCULATIONAHA.112.092312. Epub 2012 May 24.
4
Pattern of heart failure in a Nigerian teaching hospital.尼日利亚一家教学医院的心力衰竭模式。
Vasc Health Risk Manag. 2009;5:745-50. doi: 10.2147/vhrm.s6804. Epub 2009 Sep 18.
9
Echocardiographic analysis of valvular heart diseases over one decade in Nigeria.尼日利亚十年间心脏瓣膜病的超声心动图分析
Trans R Soc Trop Med Hyg. 2008 Dec;102(12):1214-8. doi: 10.1016/j.trstmh.2008.06.008. Epub 2008 Jul 21.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验