Mamalui-Hunter Maria, Li Harold, Low Daniel A
Department of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, St. Louis, Missouri 63110, USA.
Med Phys. 2008 Jun;35(6):2347-55. doi: 10.1118/1.2919560.
Amorphous silicon based electronic portal imaging devices (EPIDs) have been shown to be a good alternative to radiographic film for routine quality assurance (QA) of multileaf collimator (MLC) positioning accuracy. In this work, we present a method of acquiring an EPID image of a traditional strip-test image using analytical fits of the interleaf and leaf abutment image signatures. After exposure, the EPID image pixel values are divided by an open field image to remove EPID response and radiation field variations. Profiles acquired in the direction orthogonal to the leaf motion exhibit small peaks caused by interleaf leakage. Gaussian profiles are fitted to the interleaf leakage peaks, the results of which are, using multiobjective optimization, used to calculate the image rotational angle with respect to the collimator axis of rotation. The relative angle is used to rotate the image to align the MLC leaf travel to the image pixel axes. The leaf abutments also present peaks that are fitted by heuristic functions, in this case modified Lorentzian functions. The parameters of the Lorentzian functions are used to parameterize the leaf gap width and positions. By imaging a set of MLC fields with varying gaps forming symmetric and asymmetric abutments, calibration curves with regard to relative peak height (RPH) versus nominal gap width are obtained. Based on this calibration data, the individual leaf positions are calculated to compare with the nominal programmed positions. The results demonstrate that the collimator rotation angle can be determined as accurate as 0.01 degrees. A change in MLC gap width of 0.2 mm leads to a change in RPH of about 10%. For asymmetrically produced gaps, a 0.2 mm MLC leaf gap width change causes 0.2 pixel peak position change. Subpixel resolution is obtained by using a parameterized fit of the relatively large abutment peaks. By contrast, for symmetrical gap changes, the peak position remains unchanged with a standard deviation of 0.05 pixels, or 0.026 mm. A trial run of 36 test images, each with gap widths varying from 0.4 to 1.4 mm, were used to analyze 8640 abutments. The leaf position variations were detected with a precision of 0.1 mm at a 95% confidence level, with a mean of 0.04 mm and a standard deviation of 0.03 mm. The proposed method is robust and minimizes the effect of image noise and pixel size and may help physicists to establish reliable and reasonable action levels in routine MLC QA.
基于非晶硅的电子射野影像装置(EPID)已被证明是用于多叶准直器(MLC)定位精度常规质量保证(QA)的射线照相胶片的良好替代品。在这项工作中,我们提出了一种使用叶间和叶片邻接图像特征的解析拟合来获取传统条形测试图像的EPID图像的方法。曝光后,将EPID图像像素值除以开放野图像以消除EPID响应和辐射场变化。在与叶片运动正交的方向上获取的剖面图显示出由叶间泄漏引起的小峰值。将高斯剖面拟合到叶间泄漏峰值,其结果通过多目标优化用于计算相对于准直器旋转轴的图像旋转角度。相对角度用于旋转图像,以使MLC叶片行程与图像像素轴对齐。叶片邻接处也呈现出由启发式函数拟合的峰值,在这种情况下是修正的洛伦兹函数。洛伦兹函数的参数用于参数化叶片间隙宽度和位置。通过对一组具有不同间隙形成对称和不对称邻接的MLC射野进行成像,获得了相对峰值高度(RPH)与标称间隙宽度的校准曲线。基于该校准数据,计算各个叶片位置以与标称编程位置进行比较。结果表明,准直器旋转角度可以精确到0.01度。MLC间隙宽度变化0.2 mm会导致RPH变化约10%。对于非对称产生的间隙,MLC叶片间隙宽度变化0.2 mm会导致峰值位置变化0.2像素。通过对相对较大的邻接峰值进行参数化拟合获得亚像素分辨率。相比之下,对于对称间隙变化,峰值位置保持不变,标准偏差为0.05像素,即0.026 mm。使用36张测试图像进行试运行,每张图像的间隙宽度从0.4到1.4 mm不等,用于分析8640个邻接处。在95%置信水平下,叶片位置变化的检测精度为0.1 mm,平均值为0.04 mm,标准偏差为0.03 mm。所提出的方法具有鲁棒性,可将图像噪声和像素大小的影响降至最低,并可能有助于物理学家在常规MLC QA中建立可靠且合理的行动水平。