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一种基于电子射野影像装置(EPID)和EBT3胶片分析不同类型多叶准直器(MLC)在动态调强放射治疗(IMRT)中叶片位置和速度的定量方法。

A quantitative method to the analysis of MLC leaf position and speed based on EPID and EBT3 film for dynamic IMRT treatment with different types of MLC.

作者信息

Li Yinghui, Chen Lixin, Zhu Jinhan, Wang Bin, Liu Xiaowei

机构信息

School of Physics, Sun Yat-sen University, Guangzhou, Guangdong, China.

State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.

出版信息

J Appl Clin Med Phys. 2017 Jul;18(4):106-115. doi: 10.1002/acm2.12102. Epub 2017 May 18.

Abstract

A quantitative method based on the electronic portal imaging system (EPID) and film was developed for MLC position and speed testing; this method was used for three MLC types (Millennium, MLCi, and Agility MLC). To determine the leaf position, a picket fence designed by the dynamic (DMLC) model was used. The full-width half-maximum (FWHM) values of each gap measured by EPID and EBT3 were converted to the gap width using the FWHM versus nominal gap width relationship. The algorithm developed for the picket fence analysis was able to quantify the gap width, the distance between gaps, and each individual leaf position. To determine the leaf speed, a 0.5 × 20 cm MLC-defined sliding gap was applied across a 14 × 20 cm symmetry field. The linacs ran at a fixed-dose rate. The use of different monitor units (MUs) for this test led to different leaf speeds. The effect of leaf transmission was considered in a speed accuracy analysis. The difference between the EPID and film results for the MLC position is less than 0.1 mm. For the three MLC types, twice the standard deviation (2 SD) is provided; 0.2, 0.4, and 0.4 mm for gap widths of three MLC types, and 0.1, 0.2, and 0.2 mm for distances between gaps. The individual leaf positions deviate from the preset positions within 0.1 mm. The variations in the speed profiles for the EPID and EBT3 results are consistent, but the EPID results are slightly better than the film results. Different speeds were measured for each MLC type. For all three MLC types, speed errors increase with increasing speed. The analysis speeds deviate from the preset speeds within approximately 0.01 cm s . This quantitative analysis of MLC position and speed provides an intuitive evaluation for MLC quality assurance (QA).

摘要

开发了一种基于电子射野影像系统(EPID)和胶片的定量方法用于多叶准直器(MLC)位置和速度测试;该方法用于三种MLC类型(Millennium、MLCi和Agility MLC)。为确定叶片位置,使用了由动态(DMLC)模型设计的栅栏图案。通过EPID和EBT3测量的每个间隙的半高宽(FWHM)值利用FWHM与标称间隙宽度的关系转换为间隙宽度。为栅栏图案分析开发的算法能够量化间隙宽度、间隙之间的距离以及每个叶片的位置。为确定叶片速度,在一个14×20 cm的对称野上施加一个0.5×20 cm由MLC定义的滑动间隙。直线加速器以固定剂量率运行。此测试中使用不同的监测单位(MU)导致叶片速度不同。在速度精度分析中考虑了叶片透射的影响。MLC位置的EPID和胶片结果之间的差异小于0.1 mm。对于三种MLC类型,给出了两倍标准差(2 SD);三种MLC类型间隙宽度的2 SD分别为0.2、0.4和0.4 mm,间隙之间距离的2 SD分别为0.1、0.2和0.2 mm。各个叶片位置与预设位置的偏差在0.1 mm以内。EPID和EBT3结果的速度曲线变化是一致的,但EPID结果略优于胶片结果。每种MLC类型测量的速度不同。对于所有三种MLC类型,速度误差随速度增加而增大。分析速度与预设速度的偏差在约0.01 cm/s以内。这种对MLC位置和速度的定量分析为MLC质量保证(QA)提供了直观的评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c5b/7663986/948a2df5bc78/ACM2-18-106-g001.jpg

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