Arbuliev K M
Urologiia. 2008 Jan-Feb(1):15-20.
Forty three patients with purulent pyelonephritis complicated with abscess or pyelonephritis received local treatment with application of active carbon drainage columns made of macroporous capron net or cotton with 2.5-4 nm pores. These drains showed high efficacy both in vitro and in patients with purulent pyelonephritis. The amount of liquid evacuated from the retroperitoneal space by these drains is 10 times more than that evacuated by chlorvinyl tube. Active carbon in the column adsorbs microbial bodies and toxins from the retroperitoneal space and the kidney. Measurement of mid-molecular peptides (MMP) in patients of the study and control groups detected a sharp fall of serum MMP in the study group. The number of microbial bodies in the study group diminished from 10(10) CFU/ml to 10(3) CFU/ ml, then to 10 CFU/ml; in the controls this number decreased from 10(10) CFU/ml to 10(4-5) CFU/ml on day 7-8. Secondary nephrectomy was performed in 2 (5%) patients of the study group and in 5 (12%) patients of the control group. Lethality (2%) was only in the control group.
43例患有伴有脓肿的化脓性肾盂肾炎或肾盂肾炎的患者接受了局部治疗，使用的是由大孔卡普纶网或孔径为2.5 - 4纳米的棉质材料制成的活性炭引流柱。这些引流柱在体外以及化脓性肾盂肾炎患者体内均显示出高效性。通过这些引流柱从腹膜后间隙引出的液体量是通过氯乙烯管引出量的10倍。柱内的活性炭从腹膜后间隙和肾脏吸附微生物体及毒素。对研究组和对照组患者的中分子肽（MMP）进行测量发现，研究组血清MMP急剧下降。研究组的微生物体数量从10（10）CFU/毫升降至10（3）CFU/毫升，然后降至10 CFU/毫升；对照组在第7 - 8天，该数量从10（10）CFU/毫升降至10（4 - 5）CFU/毫升。研究组有2例（5%）患者接受了二次肾切除术，对照组有5例（12%）患者接受了二次肾切除术。死亡率（2%）仅出现在对照组。
