Tkachuk V N, Al'-Shukri S Kh, Tkachuk I N
Urologiia. 2008 Jan-Feb(1):27, 29, 31.
Finasteride effect before transurethral resection (TUR) of the prostatic gland was studied in 88 patients with prostatic adenoma (PA). Forty seven patients received prosteride (Gedeon Richter), forty one patients - proscar (MSD) in a dose 5 mg/day for 3 months. Finasteride reduced blood flow in prostatic tissue, density of the vascular plexus, epithelium/stroma coefficient from 1.26 to 0.84. This decreased intraoperative blood loss, postoperative hematuria, TUR duration, postoperative rehabilitation, number of early and late TUR complications.
对88例前列腺腺瘤患者在经尿道前列腺切除术(TUR)前使用非那雄胺的效果进行了研究。47例患者服用保列治(吉德昂·里奇特公司),41例患者服用保法止(默克公司),剂量均为5毫克/天,持续3个月。非那雄胺可减少前列腺组织中的血流、血管丛密度,上皮/基质系数从1.26降至0.84。这减少了术中失血、术后血尿、TUR持续时间、术后康复时间以及早期和晚期TUR并发症的数量。