加味四妙汤治疗60例痛风性关节炎
Treatment of 60 cases of gouty arthritis with modified Simiao Tang.
作者信息
Qiu Renbin, Shen Ruizi, Lin Dejiu, Chen Yuanlin, Ye Hongping
机构信息
Shenzhen Longgang Central Hospital, Shenzhen, Guangdong 518116, China.
出版信息
J Tradit Chin Med. 2008 Jun;28(2):94-7. doi: 10.1016/s0254-6272(08)60023-0.
OBJECTIVE
To observe the clinical effect of a modified Simiao Tang (Modified Decoction of Four Wonderful Drugs) for gouty arthritis and its influence on uric acid in blood.
METHODS
120 cases of gouty arthritis were randomly divided into the treatment group and control group with 60 cases in each group. Modified Simiao Tang (MST) was orally administered to the patients in the treatment group and allopurinol tablet was orally administered to the patients in the control group. The clinical effects of two groups were evaluated after one-week treatment and uric acid (UA) and C-reactive protein (CRP) levels in blood were determined after 1-month treatment.
RESULTS
The total effective rate in the treatment group was significantly higher than in the control group, 86.7% vs. 68.3% (P < 0.01). And the treatment group was also significantly better than the control group in decreasing UA and CRP (P < 0.05 or P < 0.01).
CONCLUSIONS
MST can significantly improve the symptoms and signs of gouty arthritis and decrease the levels of UA and CRP. It is good for gouty arthritis.
目的
观察加味四妙汤治疗痛风性关节炎的临床疗效及其对血尿酸的影响。
方法
将120例痛风性关节炎患者随机分为治疗组和对照组，每组60例。治疗组患者口服加味四妙汤，对照组患者口服别嘌醇片。治疗1周后评估两组的临床疗效，治疗1个月后测定血尿酸（UA）和血C反应蛋白（CRP）水平。
结果
治疗组总有效率显著高于对照组，分别为86.7%和68.3%（P<0.01）。治疗组在降低UA和CRP方面也显著优于对照组（P<0.05或P<0.01）。
结论
加味四妙汤能显著改善痛风性关节炎的症状和体征，降低UA和CRP水平，对痛风性关节炎有良好疗效。
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