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[多原发性扁平上皮型喉癌合并透明细胞型肾癌的罕见病例]

[The rare case of the multiple primary planoepithelial laryngeal cancer and clarocellular renal cancer].

作者信息

Olszewski Jurek, Sosnowski Marek, Zieliński Krzysztof, Kuśmierczyk Krzysztof, Słomińska Renata

机构信息

Klinika Otolaryngologii i Onkologii Laryngologicznej II Katedry Otolaryngologii UM w Łodzi.

出版信息

Otolaryngol Pol. 2008;62(3):330-4. doi: 10.1016/S0030-6657(08)70265-8.

Abstract

The authors present a rare case of the primary multiple planoepithelial laryngeal cancer and clarocellular renal cancer in a patient operated in the Clinic. The patient, called EJ., was admitted to the Clinic of Otolaryngology and Laryngological Oncology due to hoarse voice he had been suffering for 6 months. On the interview with the patient, otolaryngological and videolaryngostroboscopic examinations we diagnosed hypertrophic changes in the whole length of the right vocal fold with the fold mobility preserved. The hypertrophic changes in the right vocal fold were removed by Kleinsasser direct microlaryngoscopy. However, the histopathological examination showed carcinoma planoepitheliale keratodes infiltrans mucosae laryngis G-2. In the further treatment the patient was qualified to the dexter chordectomy by the CO2 laser. The histopathological examination confirmed the total removal of the changes within the healthy cells. After about one year from the completed laryngological treatment the patient visited the urological outpatient clinic due to pain ailments in the right lumbar part. The urographic examination and CT of the abdominal cavity showed a tumour (8 x 9 cm), in the right kidney. The patient was admitted to the 1st Clinic of Urology the Chair of Urology and qualified to the dexter nephrectomy. Following the operation the histopathological examination indicated carcinoma clarocellulare partim cysticum renis dextri. Class, Fuhrman 20, pT2 Nx Mx. The hyperplasia limited to the renal parenchyma. Cut-off lines of the ureter and vessels without neoplastic infiltration. The patient remains under constant catamnesis at the urological and laryngological outpatient clinic, no symptoms of the neoplasm relapse.

摘要

作者报告了一例在该诊所接受手术的患者,患有原发性多发性扁平上皮喉癌和透明细胞肾癌的罕见病例。患者EJ.因声音嘶哑6个月入住耳鼻咽喉科和喉肿瘤学诊所。在对患者进行问诊、耳鼻咽喉科检查和视频喉镜频闪检查后,我们诊断出右侧声带全长出现肥厚性改变,但声带活动度保留。通过克莱因萨瑟直接显微喉镜手术切除了右侧声带的肥厚性改变。然而,组织病理学检查显示为浸润性角化扁平上皮癌,喉黏膜G-2级。在进一步治疗中,患者符合通过二氧化碳激光进行右侧声带切除术的条件。组织病理学检查证实病变已在健康细胞内完全切除。在完成喉部治疗约一年后,患者因右腰部疼痛前往泌尿外科门诊就诊。尿路造影检查和腹腔CT显示右肾有一个肿瘤(8×9厘米)。患者被收治入泌尿外科第一诊所,符合右侧肾切除术的条件。手术后,组织病理学检查显示为右肾部分囊性透明细胞癌。分级,福尔曼20级,pT2 Nx Mx。增生局限于肾实质。输尿管和血管的切缘无肿瘤浸润。患者在泌尿外科和耳鼻咽喉科门诊持续接受随访,无肿瘤复发症状。

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