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γ-氨基丁酸对野蛞蝓前脑网络振荡的影响。

The effects of GABA on the network oscillations of the procerebrum in Limax valentianus.

作者信息

Kobayashi S, Hattori Mariko, Ito E

机构信息

Laboratory of Functional Biology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1 Shido, Sanuki, Kagawa, 769-2193, Japan.

出版信息

Acta Biol Hung. 2008;59 Suppl:77-9. doi: 10.1556/ABiol.59.2008.Suppl.12.

DOI:10.1556/ABiol.59.2008.Suppl.12
PMID:18652376
Abstract

Gamma-aminobutyric acid (GABA)-containing neurons are capable of controlling network oscillations and their patterns in the widely divergent species. In the terrestrial slug, Limax valentianus, oscillatory activity of the procerebrum neurons is considered to encode the odor information. Previous studies showed that GABA is present in the central nervous system and may be involved in the control of neuronal activity of Limax. In the present study, we examined the effects of GABA on the generation of oscillatory activity in the procerebrum. The results suggest that the GABAergic synaptic transmission may be involved in the oscillatory neural network of the procerebrum.

摘要

含γ-氨基丁酸(GABA)的神经元能够控制广泛不同物种的网络振荡及其模式。在陆生蛞蝓加州半蛞蝓中,前脑神经元的振荡活动被认为编码气味信息。先前的研究表明,GABA存在于中枢神经系统中,可能参与了对加州半蛞蝓神经元活动的控制。在本研究中,我们研究了GABA对前脑振荡活动产生的影响。结果表明,GABA能突触传递可能参与了前脑的振荡神经网络。

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