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向豚鼠注射中性硫醇蛋白酶后腹膜渗出液的细胞成分。

The cell content of peritoneal exudates following the injection of neutral thiol protease into guinea pigs.

作者信息

Hamajima F, Yamakami K, Fukuda K, Tsuru S, Fujino T, Hamajima H

机构信息

Department of Parasitology, National Defense Medical College, Tokorozawa, Japan.

出版信息

J Parasitol. 1991 Aug;77(4):635-7.

PMID:1865274
Abstract

The cell content of the peritoneal exudate was examined 4 days after an intraperitoneal injection of glycogen in uninfected and Paragonimus westermani-infected guinea pigs. In uninfected animals a reduction in macrophage count and an accumulation of granulocytes in the exudate were observed at 3 and 6 hr after an intraperitoneal injection of purified neutral thiol protease from P. westermani metacercariae. No such effect occurred after the enzyme was injected into infected animals. At 9 hr after enzyme injection, vacuoles were found in the cytoplasm of macrophages in uninfected animals.

摘要

在未感染和感染卫氏并殖吸虫的豚鼠腹腔内注射糖原4天后,检查腹腔渗出液的细胞成分。在未感染的动物中,腹腔注射来自卫氏并殖吸虫尾蚴的纯化中性硫醇蛋白酶后3小时和6小时,观察到渗出液中巨噬细胞数量减少和粒细胞积聚。将该酶注射到感染动物体内后未出现这种效应。在注射酶后9小时,在未感染动物的巨噬细胞胞质中发现了空泡。

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