Young Tim M, Mathias Christopher J
Neurovascular Medicine Unit, Faculty of Medicine, Imperial College London at St. Mary's Hospital, United Kingdom.
Auton Neurosci. 2008 Dec 5;143(1-2):77-8. doi: 10.1016/j.autneu.2008.06.003. Epub 2008 Jul 24.
Supine hypertension and post-prandial hypotension are associated with chronic autonomic failure, and may prove resistant to treatment. We determined if the hypotensive effects of food could be utilised to reduce supine hypertension in pure autonomic failure (PAF).
A subject with long-standing PAF, documented supine hypertension and post-prandial hypotension had a gastrostomy tube placed for dysphagia. We compared 24-hour ambulatory blood pressure recordings before and after nocturnal gastrostomy feeding.
Gastrostomy feeding was associated with resolution of supine hypertension and normalization of circadian BP rhythm.
Gastrostomy feeding at night may help reduce supine hypertension in autonomic failure.
仰卧位高血压和餐后低血压与慢性自主神经功能衰竭相关，且可能对治疗有抵抗性。我们确定食物的降压作用是否可用于降低单纯自主神经功能衰竭（PAF）患者的仰卧位高血压。
一名患有长期PAF、有记录的仰卧位高血压和餐后低血压的受试者因吞咽困难放置了胃造瘘管。我们比较了夜间胃造瘘管喂食前后的24小时动态血压记录。
胃造瘘管喂食与仰卧位高血压的缓解及昼夜血压节律的正常化相关。
夜间胃造瘘管喂食可能有助于降低自主神经功能衰竭患者的仰卧位高血压。
