Kobayashi Jun'ichi
Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
J Antibiot (Tokyo). 2008 May;61(5):271-84. doi: 10.1038/ja.2008.39.
This review covers the recent results described in our publications on several new cytotoxic macrolides isolated from dinoflagellates of the genus Amphidinium in addition to an overview of the isolation, structure elucidation, synthesis, biosynthesis, and bioactivity of a series of cytotoxic macrolides, named amphidinolides, reported so far.
本综述涵盖了我们发表的关于从扁藻属双鞭毛虫中分离出的几种新型细胞毒性大环内酯类化合物的最新研究成果，此外还概述了迄今为止报道的一系列名为扁藻素的细胞毒性大环内酯类化合物的分离、结构解析、合成、生物合成及生物活性。
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