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脑电图引导下切除胚胎发育不良性神经上皮肿瘤:病例报告

Electroencephalography-guided resection of dysembryoplastic neuroepithelial tumor: case report.

作者信息

Imataka George, Ogino Masahiro, Nakagawa Eiji, Yamanouchi Hideo, Arisaka Osamu

机构信息

Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan.

出版信息

Neurol Med Chir (Tokyo). 2008 Jul;48(7):318-21. doi: 10.2176/nmc.48.318.

Abstract

A 3-year-old girl presented with a dysembryoplastic neuroepithelial tumor in the right cingulate gyrus manifesting as epilepsy refractory to anticonvulsant medication. Computed tomography and magnetic resonance imaging revealed a cystic tumor in the right cingulate gyrus. The tumor was removed under intraoperative electrocorticography guidance. Abnormal spikes recorded adjacent to the tumor disappeared immediately after total removal. Histological examination showed a multinodular, multicystic structure, satisfying the criteria for the diagnosis of dysembryoplastic neuroepithelial tumor. She has remained seizure-free for more than 4 years without complications. In this case, intraoperative electrocorticography was very useful to identify the possible focus and prevent unnecessary resection of the adjacent tissue. Total removal of the tumor resulted in a dramatic reduction of seizure activity.

摘要

一名3岁女童患有位于右侧扣带回的胚胎发育不良性神经上皮肿瘤,表现为对抗癫痫药物难治的癫痫。计算机断层扫描和磁共振成像显示右侧扣带回有一个囊性肿瘤。该肿瘤在术中脑电描记图引导下被切除。肿瘤附近记录到的异常棘波在完全切除后立即消失。组织学检查显示为多结节、多囊性结构,符合胚胎发育不良性神经上皮肿瘤的诊断标准。她已无癫痫发作超过4年且无并发症。在该病例中,术中脑电描记图对于确定可能的病灶及防止不必要的邻近组织切除非常有用。肿瘤的完全切除导致癫痫活动显著减少。

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