Chernyshev A L, Filimonov R M, Karasev A V, Neronov V A, Maksimov V A
Vopr Kurortol Fizioter Lech Fiz Kult. 2008 May-Jun(3):19-22.
Patients with viral hepatitis have disturbances of biliary tract motor function with the tendency to hypertonus of Oddi's sphincter, changes of physic-colloid properties of bile with increase in density of gall and hepatic bile, pH shift to acid side, microlites formation, disorders in biochemical composition of bile. More than 80% patients have biliar insufficiency. According to our data, with the purpose to correct of disturbances of hepatic exocrine function in patients with viral hepatitis and to prevent stone formation, it is reasonable to use together with antiviral therapy also intravenous injection of ozonated physiological solution and preparations of ursodeoxycholic acid.
病毒性肝炎患者存在胆道运动功能紊乱,伴有奥狄氏括约肌张力亢进倾向,胆汁的物理 - 胶体性质发生改变,胆囊胆汁和肝胆汁密度增加,pH值向酸性偏移,形成微结石,胆汁生化成分紊乱。超过80%的患者存在胆汁分泌不足。根据我们的数据,为纠正病毒性肝炎患者肝脏外分泌功能紊乱并预防结石形成,在抗病毒治疗的同时,联合静脉注射臭氧生理盐水和熊去氧胆酸制剂是合理的。