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[小肠疾病慢性期的发展机制]

[Mechanisms of the development of the chronic phase of diseases of the small intestine].

作者信息

Parfenov A I, Ekisenina N I, Krums L M

出版信息

Klin Med (Mosk). 1991 Apr;69(4):102-5.

PMID:1865636
Abstract

The results of studying mechanisms underlying chronicity of functional (chronic enteritis ) and severe organic (celiac disease) lesions of the small intestine have been analyzed. Mechanisms causing the diseases take a chronic course appeared very similar. They involve bacterial proliferation in the intestine with consequent impairment of the digestion, absorption and motility resultant in derangement of metabolism. Defects in protein and lipid metabolism proved most essential. Chronic enteritis is associated with a favorable outcome provided there are no grave malabsorption symptoms. Combined treatment as a rule produces good therapeutic response in chronic enteritis and celiac disease. Relevant schemes are presented.

摘要

对小肠功能性(慢性肠炎)和严重器质性(乳糜泻)病变慢性化潜在机制的研究结果进行了分析。导致这些疾病呈慢性病程的机制显得非常相似。它们涉及肠道细菌增殖,进而损害消化、吸收和运动功能,导致代谢紊乱。蛋白质和脂质代谢缺陷被证明最为关键。如果没有严重的吸收不良症状,慢性肠炎预后良好。通常联合治疗对慢性肠炎和乳糜泻有良好的治疗反应。文中给出了相关方案。

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