[Thrombolytic therapy in acute myocardial infarction at the pre-hospital stage].

Mobile teams of the Leningrad Emergency Station came to use prehospital thrombolytic therapy (TT) for acute myocardial infarction (AMI) in 1986. The trial reported includes three groups of AMI patients: group I of 67 patients received avelysin in a dose of 0.5 mln FU, group II of 35 patients received celyase in a dose of 1 mln FU, group III consisted of 47 control subjects. The analysis of the treatment results showed that intravenous infusion of avelysin enabled myocardial reperfusion in 49.3% of cases while that of celyase in 5.7% (noninvasive data). High effectiveness of avelysin is inferred as well as safety of systemic TT at prehospital stage of AMI.