Kleĭner A I, Shmuter L M, Makotchenko V M, Efremova V A, Khodzhaĭ Ia I, Trukh V S
Klin Med (Mosk). 1991 Apr;69(4):58-60.
A positive immunomodulatory effect was found in chronic bronchitis patients examined immunologically before and after treatment including chlotazol. T- and B-cell immunity recovered, clinical condition of the patients improved. A combination of known antimicrobial and antiinflammatory effects with an uncovered immunomodulatory one made chlotazol a valuable modality in the treatment of chronic bronchitis associated with secondary immune deficiency.