[抗乙肝核心抗原 IgM 在乙型肝炎中的诊断及预后意义及其结果]
[Diagnostic and prognostic significance of anti-HBCAG IgM in hepatitis B and its outcomes].
作者信息
Fedorchenko S V
出版信息
Klin Med (Mosk). 1991 Apr;69(4):66-8.
PMID:1865655
Abstract
Enzyme immunoassay was employed to investigate HBV markers (HBsAg, HBeAg, IgM anti-HBc, anti-HBc, anti-HBs) in 126 patients suffering from viral hepatitis B. It was noted that IgM anti-HBc appeared in ++pre-jaundice period in 100% of the examinees. In case of hepatitis transformation into a chronic form the titers of IgM anti-HBc depended on the disease activity, their high concentration being typical for the stage of active virus replication.
摘要
采用酶免疫分析法对126例乙型病毒性肝炎患者的乙肝标志物（乙肝表面抗原、乙肝e抗原、抗乙肝核心抗体IgM、抗乙肝核心抗体、抗乙肝表面抗体）进行检测。结果发现，100%的受检者在黄疸前期IgM抗乙肝核心抗体呈阳性。在肝炎转变为慢性的情况下，IgM抗乙肝核心抗体的滴度取决于疾病活动度，其高浓度在病毒活跃复制阶段较为典型。
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