Marcus Daniel B, Lee Paul C, Fish David E
Santa Cruz Medical Foundation Department of Physical Medicine, Santa Cruz, California 95065, USA.
Pain Med. 2008 Oct;9(7):866-70. doi: 10.1111/j.1526-4637.2008.00479.x. Epub 2008 Jul 24.
To report a case in which pain preceded computer axial tomography (CT) and scintigraphic findings in an osteoporotic vertebral compression fracture.
DESIGN/SETTING: Report of a patient presenting to a physical medicine/pain medicine outpatient clinic.
Eighty-seven-year-old female with history of osteoporosis and previous vertebral compression fracture with new onset, atraumatic, axial thoracic pain.
Thoracic spine CT, bone scintigraphy, kyphoplasty (Kyphon-Medtronic, Sunnyvale, CA).
Not applicable.
History and physical exam were suggestive of thoracic compression fracture. CT and bone scintigraphy were negative for vertebral compression fracture. A CT of the pulmonary arteries during an unrelated hospital admission less than two weeks after initial presentation revealed a compression fracture at T7. Pain report was unchanged except for an increase in intensity. Follow-up X-ray and CT revealed a compression fracture at T7 with loss of 80% of vertebral height. Pain was successfully treated with kyphoplasty.
CT and bone scintigraphy performed early after pain onset did not reveal a vertebral compression fracture. Within 2 weeks, fracture was evident on further imaging. The pain resolved following an intervention directed at the fracture.
The patient's pain preceded CT and scintigraphic evidence of the osteoporotic vertebral compression fracture. It is possible that pain is an early sign of impending osteoporotic compression fracture, or microtrabecular fracture, prior to anatomic and physiologic changes. Magnetic resonance imaging may be the imaging study of choice rather than bone scintigraphy in identification of noncollapsed osteoporotic compression fracture. Earlier identification and treatment of vertebral compression fractures may reduce kyphosis and associated sequelae.
报告一例骨质疏松性椎体压缩骨折患者,其疼痛先于计算机断层扫描(CT)和骨闪烁显像结果出现。
设计/背景:对一名前往物理医学/疼痛医学门诊就诊患者的报告。
87岁女性,有骨质疏松病史及既往椎体压缩骨折史,新发非创伤性胸背部轴向疼痛。
胸椎CT、骨闪烁显像、椎体后凸成形术(美敦力公司,加利福尼亚州桑尼维尔市生产的Kyphon)。
不适用。
病史和体格检查提示胸椎压缩骨折。CT和骨闪烁显像显示椎体压缩骨折为阴性。在初次就诊后不到两周的一次无关住院期间,肺动脉CT显示T7椎体压缩骨折。除疼痛强度增加外,疼痛报告无变化。随访X线和CT显示T7椎体压缩骨折,椎体高度丢失80%。椎体后凸成形术成功治疗了疼痛。
疼痛发作后早期进行的CT和骨闪烁显像未显示椎体压缩骨折。在2周内,进一步影像学检查显示骨折明显。针对骨折进行干预后疼痛缓解。
患者的疼痛先于骨质疏松性椎体压缩骨折的CT和闪烁显像证据出现。疼痛可能是即将发生的骨质疏松性压缩骨折或微小梁骨折的早期迹象,早于解剖和生理变化。在识别未塌陷的骨质疏松性压缩骨折方面,磁共振成像可能是比骨闪烁显像更合适的影像学检查方法。更早地识别和治疗椎体压缩骨折可能会减少脊柱后凸及相关后遗症。