Di Bartolomeo Stefano, Valent Francesca, Sanson Gianfranco, Nardi Giuseppe, Gambale Giorgio, Barbone Fabio
Cattedra di Epidemiologia, University of Udine, Via Colugna 40, 33100 Udine, Italy.
Injury. 2008 Sep;39(9):1001-6. doi: 10.1016/j.injury.2008.04.009. Epub 2008 Jul 26.
Quality indicators are widely needed for external assessment and comparison of trauma care. It is common to extend the use of the American College of Surgeons Committee on Trauma (ACSCOT) audit filters to this scope. This mandates that their actual link with outcome be demonstrated. Several studies attempted to do so, but with inconsistent risk-adjustment, conflicting results and never using long-term disability as outcome measure, despite its recognised importance. We tried to overcome these limitations.
Risk-adjusted analysis of the association of filters 1, 3, 10 and 13 with 30-day mortality and 6-month disability measured with the EQ5D scale. Multivariate logistic and linear regression models were used respectively. The data came from a National Italian Trauma Registry comprising 838 patients with major trauma.
Three (1, 3 and 10) of the filters analysed did not show any significant association with either outcome. Filter 13 was associated with decreased mortality and lower (worse) disability scores.
Methodological difficulties, incomplete, obsolete or non-generalizable definitions of some filters can explain the generally poor correlation with outcomes. The conflicting association of filter 13 with the two types of outcomes raises some interesting questions about the targeted outcomes in trauma research. It is recommended that further studies develop better quality indicators and test their link with both survival and functional outcome in the same setting where they are applied for assessment and comparison of trauma care.
创伤护理的外部评估和比较广泛需要质量指标。将美国外科医师学会创伤委员会(ACSCOT)的审计筛选标准扩展到这一范围很常见。这就要求证明它们与结果之间的实际联系。多项研究试图这样做,但风险调整不一致、结果相互矛盾,且尽管长期残疾作为结果指标的重要性已得到认可,但从未将其用作结果指标。我们试图克服这些局限性。
对筛选标准1、3、10和13与30天死亡率以及用EQ5D量表测量的6个月残疾之间的关联进行风险调整分析。分别使用多变量逻辑回归和线性回归模型。数据来自一个包含838例严重创伤患者的意大利国家创伤登记处。
所分析的筛选标准中有三个(1、3和10)与任何一种结果均无显著关联。筛选标准13与死亡率降低和较低(较差)的残疾评分相关。
方法上的困难、一些筛选标准定义不完整、过时或不可推广,可以解释其与结果之间普遍较差的相关性。筛选标准13与两种类型结果之间相互矛盾的关联,引发了一些关于创伤研究中目标结果的有趣问题。建议进一步的研究开发出质量更好的指标,并在应用于创伤护理评估和比较的相同环境中测试它们与生存和功能结果之间的联系。