Zografos George C, Zagouri Flora, Sergentanis Theodoros N, Nonni Afrodite, Domeyer Philip, Koulocheri Dimitra, Flessas Ioannis, Panopoulou Effrosyni, Chrysikos Dimosthenis, Bramis John
Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, University of Athens, 114 Vas Sofias Avenue, Athens 116 27, Greece.
Breast. 2008 Dec;17(6):592-5. doi: 10.1016/j.breast.2008.06.002. Epub 2008 Jul 26.
To assess the putative predictors that may be implicated in the pain experienced during stereotactic vacuum-assisted breast biopsy (VABB).
One hundred and thirty-five consecutive women with microcalcifications underwent VABB on the Fischer's table. The visual analogue scale was used to measure the degree of the "average pain" (AP).
At the univariable analysis, the AP was positively associated with the duration of the procedure, the diagnosis of malignant/preinvasive lesions and the volume of blood lost. Although menopausal status was not associated with the AP, within the premenopausal subpopulation, luteal phase was associated with higher VAS score. These findings also persisted at the multivariable ordinal logistic regression model. However, the mean experienced pain was associated neither with the volume of tissue excised nor with the hematoma formation, nor with patients' age.
The aforementioned factors were independent positive predictors of the mean experienced pain during VABB.
评估可能与立体定向真空辅助乳腺活检（VABB）过程中所经历疼痛相关的假定预测因素。
135例连续的有微钙化的女性在费舍尔手术台上接受了VABB。采用视觉模拟量表来测量“平均疼痛”（AP）程度。
在单变量分析中，AP与手术持续时间、恶性/浸润前病变的诊断以及失血量呈正相关。虽然绝经状态与AP无关，但在绝经前亚组中，黄体期与较高的视觉模拟量表评分相关。这些发现也在多变量有序逻辑回归模型中持续存在。然而，平均经历的疼痛与切除组织的体积、血肿形成以及患者年龄均无关。
上述因素是VABB过程中平均经历疼痛的独立阳性预测因素。
