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腺样体扁桃体切除术后发病率中抗生素的使用:一项随机前瞻性研究。

Antibiotic use in post-adenotonsillectomy morbidity: a randomized prospective study.

作者信息

Guerra Marja Michelin, Garcia Eduardo, Pilan Renata Ribeiro de Mendonça, Rapoport Priscila Bogar, Campanholo Caio Barbosa, Martinelli Eli Onivaldo

机构信息

FMABC, Brazil.

出版信息

Braz J Otorhinolaryngol. 2008 May-Jun;74(3):337-41. doi: 10.1016/s1808-8694(15)30565-6.

Abstract

UNLABELLED

Tonsillectomy with or without adenoidectomy still is one of the most commonly performed surgical procedures in the world, mostly in the pediatric population.

AIM

to study the impact of amoxicillin for 7 days in post-adenotonsillectomy recovery, comparing results with a control group.

STUDY TYPE

prospective, randomized, controlled study with 120 patients.

PATIENTS AND METHODS

the patients were randomized according to surgery time to receive 7 days of amoxicillin associated with pain killers, or analgesic alone. During the first week of postoperative, we assessed the level of pain, oral intake acceptance, nausea and vomits, fever and return to daily activities.

RESULTS

It was only in the fourth post-operative day that the group receiving antibiotic agents showed a statistically significant difference as far as pain is concerned. There was no difference between the two groups for other data analyzed.

CONCLUSION

considering the results from our study and reviewing the literature on the use of antibiotic agents, we agree that there is no improvement in patient recovery after adenotonsillectomy with the use of amoxicillin for 7 days in the postoperative.

摘要

未标注

扁桃体切除术(伴或不伴腺样体切除术)仍是世界上最常施行的外科手术之一,主要针对儿童群体。

目的

研究阿莫西林连续使用7天对腺样体扁桃体切除术后恢复的影响,并与对照组结果进行比较。

研究类型

对120例患者进行的前瞻性、随机、对照研究。

患者与方法

根据手术时间将患者随机分组,一组接受7天阿莫西林联合止痛剂治疗,另一组仅接受止痛剂治疗。术后第一周,我们评估了疼痛程度、口服摄入量接受情况、恶心和呕吐情况、发热情况以及恢复日常活动的情况。

结果

仅在术后第四天,接受抗生素治疗的组在疼痛方面显示出统计学上的显著差异。两组在其他分析数据方面无差异。

结论

考虑到我们的研究结果并回顾关于使用抗生素的文献,我们一致认为,术后使用阿莫西林7天对腺样体扁桃体切除术后患者的恢复并无改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e5b/9442118/9acdc4e78674/gr1.jpg

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