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帕金森病患者的神经耳科学表现

Neurotological findings in patients with Parkinson's disease.

作者信息

Bassetto Jackeline Martins, Zeigelboim Bianca Simone, Jurkiewicz Ari Leon, Klagenberg Karlin Fabianne

出版信息

Braz J Otorhinolaryngol. 2008 May-Jun;74(3):350-5. doi: 10.1016/s1808-8694(15)30567-x.

Abstract

UNLABELLED

The number of elderly people is increasing considerably in our settings, and with that we have a matching increase in chronic-degenerative diseases - such as Parkinson's Disease (PD), which has balance-related symptoms associated and is increasingly more prevalent in the elderly population.

AIM

Study labyrinth exams in PD patients and associate them with vestibular disorders.

STUDY DESIGN

contemporary cross-sectional cohort.

MATERIALS AND METHODS

Thirty patients were assessed, twenty females and ten males, at the age range of 48 - 84 years.

PROCEDURES

anamnesis, ear inspection and vestibular assessment by means of a vecto-electronystagmography (VENG).

RESULTS

a) As to the neurotological complaints reported in the anamnesis, there was a prevalence of: tremor (100.0%), dizziness (43.3%), tinnitus (40.0%), gait unbalance and falls (36.6%) in each; b) in assessing the vestibular function, there was a significant difference in the rate of altered exams (p=0.0000); c) Most alterations happened in the peripheral vestibular system (93.3%) and the caloric test, with a predominance of bilateral labyrinth hyporreflexia (30,0%); d) The exam results were correlated with the vestibular symptoms and we noticed that there were no significant differences.

CONCLUSION

this study showed us a significant number of altered exams, unrelated to symptoms.

摘要

未标注

在我们的环境中,老年人数量正在大幅增加,随之而来的是慢性退行性疾病的相应增加——比如帕金森病(PD),它伴有与平衡相关的症状,且在老年人群中越来越普遍。

目的

研究帕金森病患者的内耳检查,并将其与前庭疾病相关联。

研究设计

当代横断面队列研究。

材料与方法

评估了30名患者,其中20名女性,10名男性,年龄在48 - 84岁之间。

程序

通过病史采集、耳部检查以及采用矢量眼震电图(VENG)进行前庭评估。

结果

a)关于病史采集中报告的神经耳科主诉,每种症状的患病率分别为:震颤(100.0%)、头晕(43.3%)、耳鸣(40.0%)、步态失衡和跌倒(36.6%);b)在评估前庭功能时,检查结果异常率存在显著差异(p = 0.0000);c)大多数异常发生在外周前庭系统(93.3%)和冷热试验中,以双侧迷路反应减退为主(30.0%);d)检查结果与前庭症状相关,且我们注意到没有显著差异。

结论

本研究向我们展示了大量与症状无关的异常检查结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035e/9442055/b187b7303ada/gr1.jpg

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