Zhang Xin-Guang, Wang Dong-Mei, Huang Qian
People's hospital of Dongguan, Dongguan 523018, China.
Zhong Yao Cai. 2008 Apr;31(4):594-7.
To study the technology of optimal extraction for Tiao ZhiAn mixture.
Optimization of the influence of the mixed volatile oil extracting of Ligusticum chuanxiong Hort., Angelica sinensis (Oliv.) Diels and Curcuma longa L. was chosen by single-index test. Orthogonal test was employed for selecting the optimum of extraction technology by colligation score as the indexes of the contents of stilbene glucoside of Polygunum multiflorum Thunb, total solid matters in water extraction.
The best technology for extracting Ligusticum chuanxiong Hort., Angelica sinensis (oliv.) Diels and Curcuma longa L. was to add water nine times within eight hours. The way of adding water six times to the medicine sediment and other herbs, extracting 3 times in one hour each time was considered the optimum extraction technology.
The considerable extraction rate of active components in the drugs is achieved by applying the selected technology, and the simple method is fit for manufacturing Tiao ZhiAn mixture.
研究调脂安合剂的最佳提取工艺。
采用单指标试验对川芎、当归、姜黄混合挥发油提取的影响因素进行优化。以何首乌中二苯乙烯苷含量、水提取物中总固体物为指标,采用综合评分法,通过正交试验筛选最佳提取工艺。
川芎、当归、姜黄最佳提取工艺为8小时内加水9倍量。药渣及其他药材加水6倍量,每次1小时,提取3次为最佳提取工艺。
采用所选工艺可使药物中有效成分提取率较高,该方法简便,适合调脂安合剂的生产。