Roy D, Kulkarni A, Kulkarni S, Thakur M H, Maheshwari A, Tongaonkar H B
Department of Radiodiagnosis, Genitourinary and Gynaec Oncology Services, Tata Memorial Hospital, Mumbai, India.
Br J Radiol. 2008 Nov;81(971):902-6. doi: 10.1259/bjr/56205669. Epub 2008 Jul 28.
The objective of this study was to evaluate the feasibility, safety and diagnostic accuracy of transrectal ultrasound (TRUS)-guided core biopsy for recurrent carcinoma of the uterine cervix in patients with non-diagnostic vaginal cytology and transvaginal punch biopsy.17 patients with clinical and imaging suspicion of recurrent carcinoma of the cervix, and with negative cytology and punch biopsy, were referred for TRUS-guided biopsy of a recurrent mass. Data were collected with respect to demography, previous diagnosis, treatment received, size and location of the recurrent lesion, and biopsy results. Adequate samples were obtained for all patients. TRUS-guided biopsy was technically successful in all of the patients and provided histological diagnosis of recurrence in 16 patients. One of the patients had post-radiation fibrosis. There were no procedure-related complications. In conclusion, TRUS-guided biopsy for recurrent cervical cancer is a feasible, safe and accurate method for establishing a histopathological diagnosis. It should be considered in patients with non-diagnostic vaginal cytology and punch biopsy.
本研究的目的是评估经直肠超声（TRUS）引导下的核心活检对于阴道细胞学检查和经阴道穿刺活检无法明确诊断的子宫颈复发癌患者的可行性、安全性及诊断准确性。17例临床及影像学怀疑为子宫颈复发癌，但细胞学检查及穿刺活检结果为阴性的患者被转诊接受TRUS引导下对复发肿块的活检。收集了有关人口统计学、既往诊断、接受的治疗、复发病变的大小和位置以及活检结果的数据。所有患者均获得了足够的样本。TRUS引导下的活检在所有患者中技术操作均成功，16例患者获得了复发的组织学诊断。其中1例患者为放疗后纤维化。未发生与操作相关的并发症。总之，TRUS引导下对复发性宫颈癌进行活检是一种可行、安全且准确的建立组织病理学诊断的方法。对于阴道细胞学检查和穿刺活检无法明确诊断的患者应考虑采用该方法。
