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国际原子能机构(IAEA)项目对泰国辐射与组织库的影响。

The impact of the International Atomic Energy Agency (IAEA) program on radiation and tissue banking in Thailand.

作者信息

Vajaradul Yongyudh, Morales Pedraza Jorge

机构信息

Bangkok Biomaterial Centre, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Cell Tissue Bank. 2009 May;10(2):125-32. doi: 10.1007/s10561-008-9087-y. Epub 2008 Jul 29.

DOI:10.1007/s10561-008-9087-y
PMID:18663602
Abstract

Tissue banking started in Thailand in 1979. Five years after this, the Bangkok Biomaterial Centre (BBC) was established in the Faculty of Medicine, Siriraj Hospital, with the support of the IAEA program. The objective of the Centre was to provide sterile bones and tissues for clinical use. Through the passage of time, the Bangkok Biomaterial Centre has gained confidence from the end user and by 2007 has processed 33,872 allografts from 491 deceased donors and 4,035 live donors were used in medical treatment in 3,596 patients in more than 79 different hospitals. More than 305 surgeons from Thailand used the tissue produced in the BBC. At the beginning of its work the BBC concentrate its activities on the production of the following tissues: freeze dried bone, freeze dried dura mater and freeze dried fascia lata. All of these tissues were sterilised using ethylene oxide gas until the end of year 1984. Since 1985 the BBC sterilise tissue using ionising radiation. The BBC is now producing deep-frozen; bone tendon, cartilage, trachea and soft tissue; freeze-dried; bone, fascia lata, dura mater, amniotic membrane, bone hydroxyapatite, bone tablet and fresh preserved amniotic membrane.

摘要

组织库于1979年在泰国起步。在此五年后,曼谷生物材料中心(BBC)在诗里拉吉医院医学院成立,得到了国际原子能机构项目的支持。该中心的目标是提供无菌骨骼和组织用于临床。随着时间的推移,曼谷生物材料中心赢得了终端用户的信任,到2007年,已处理了来自491名已故捐赠者的33872份同种异体移植物,4035名活体捐赠者的组织被用于79多家不同医院的3596名患者的治疗。超过305名泰国外科医生使用了BBC生产的组织。在其工作初期,BBC将活动集中在以下组织的生产上:冻干骨、冻干硬脑膜和冻干阔筋膜。直到1984年底,所有这些组织都使用环氧乙烷气体进行灭菌。自1985年以来,BBC使用电离辐射对组织进行灭菌。BBC现在生产深度冷冻的;骨肌腱、软骨、气管和软组织;冻干的;骨、阔筋膜、硬脑膜、羊膜、骨羟基磷灰石、骨片和新鲜保存的羊膜。

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