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[骨筋膜室综合征的病理生理学与压力测量]

[Pathophysiology and pressure measurement in compartment syndrome].

作者信息

Scola E

机构信息

Unfallchirurgische Klinik, Medizinischen Hochschule Hannover.

出版信息

Unfallchirurg. 1991 May;94(5):220-4.

PMID:1866634
Abstract

Traumatic or ischemic damage of the musculature and soft tissue may cause compartment syndrome. In trauma, mechanical influences provoke humeral disorders and liberation of vasoactive substances with early onset of compartment syndrome, but isolated total ischemia of more than 6 h is commonly followed after revascularization by compartment syndrome caused by post-ischemic dilation of vessels. An understanding of the pathophysiology in compartment syndrome provides a better possibility of predicting this severe complication in trauma and vascular surgery patients. Several techniques are described for intracompartmental pressure monitoring. In normotensive patients, an intracompartmental pressure of more than 40 mmHg indicates "apparent" compartment syndrome, while pressures between 30 mmHg and 40 mmHg are interpreted as "imminent" compartment syndrome. In these cases therapeutic/prophylactic dermatofasciotomy is necessary. In hypotensive patients the lower limit for conducting a dermatofasciotomy must be reduced. According to the pathophysiology, an intracompartmental pressure of about 30 mmHg for more than 6 h duration must be treated by dermatofasciotomy.

摘要

肌肉组织和软组织的创伤性或缺血性损伤可能导致骨筋膜室综合征。在创伤中,机械性影响会引发肱骨疾病并释放血管活性物质,从而导致骨筋膜室综合征早期发作,但血管再通后,超过6小时的孤立性完全缺血通常会继发于缺血后血管扩张引起的骨筋膜室综合征。了解骨筋膜室综合征的病理生理学,有助于更好地预测创伤和血管手术患者的这种严重并发症。文中描述了几种骨筋膜室内压力监测技术。在血压正常的患者中,骨筋膜室内压力超过40 mmHg表明存在“明显”的骨筋膜室综合征,而压力在30 mmHg至40 mmHg之间则被解释为“即将发生”的骨筋膜室综合征。在这些情况下,有必要进行治疗性/预防性皮肤筋膜切开术。在低血压患者中,进行皮肤筋膜切开术的下限必须降低。根据病理生理学,骨筋膜室内压力约30 mmHg持续超过6小时必须通过皮肤筋膜切开术进行治疗。

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