Gregersen P L, Ottovay E, Kobayashi C, Hansen S E, Bohnstedt J
Sønderborg Sygehus, øjenafdelingen.
Ugeskr Laeger. 1991 Jul 22;153(30):2123-4.
Forty patients with corneal epithelial defects were randomized into two groups. Group 1 (twenty patients) were treated with chloramphenicol ointment and an eye patch for six hours followed by chloramphenicol eyedrops six time a day for six days. Group 2 (twenty patients) were treated with chloramphenicol ointment and double eye patches for twenty-four hours as the only treatment. The patients were examined the next day, and again after a week. Two patients defected in group 1 and two patients from group 1 were excluded from the experiment because they failed to improve after three and four days, respectively. Five patients from group 2 defected. Corneal epithelial wound healing was found to be significantly faster in the group treated with double eye patches and the patients' subjective problems in this group were significantly less. (Significant with a probability less than 1%).
40例角膜上皮缺损患者被随机分为两组。第1组（20例患者）用氯霉素眼膏和眼罩治疗6小时，随后每天6次滴用氯霉素滴眼液，共6天。第2组（20例患者）仅用氯霉素眼膏和双眼罩治疗24小时。次日对患者进行检查，1周后再次检查。第1组有2例患者退出，第1组另有2例患者被排除在实验之外，因为他们分别在3天和4天后病情未改善。第2组有5例患者退出。结果发现，使用双眼罩治疗的组角膜上皮伤口愈合明显更快，且该组患者的主观问题明显更少。（显著性概率小于1%）
