Olesgaard P
Ugeskr Laeger. 1991 Jul 29;153(31):2158-60.
On the basis of increased interest by the Danish public, not only popularly but also professionally, for generic prescription, a review of the subject is presented. In USA, in particular, pronounced opposition to generic prescription exists from the medical profession and from the drug industry. It is considered that the incitement to develop an original product is weakened. It is feared that marketed "synonymous" product are not always synonymous. Investigation have been carried out to show that generic prescription can function to the satisfaction of everyone and parcticularly the consumers' satisfaction (up to 83% of the patients express satisfaction with arrangement in a Danish investigation). In addition, the system results in an immediate saving (approximately 7%), if it functions. However, at its best, the system functions in only half of the cases in the majority of places, in USA most frequently only in 10% and in England in 36%. The professional groups constitute the greatest obstacle. Doctors, in particular, show great doubts about the advisability of the system. If the system is to function at all, pharmacologists and doctors must be motivated to employ the system correctly. Education is necessary in order to avoid generic prescription involving considerable unpaid extra work for the pharmacist and the doctor. It is essential that the Danish Board of Health can guarantee that synonymous preparations on the market are, in fact, synonymous. Finally, decisions about the extent to which synonymous preparations may be dispensed must lie in the hands of the prescribing doctor who is responsible for the prescription.
基于丹麦公众（不仅是普通民众，还有专业人士）对通用处方兴趣的增加，本文对该主题进行了综述。特别是在美国，医学界和制药行业对通用处方存在明显的反对意见。人们认为开发原创产品的动力被削弱了。有人担心上市的“同义词”产品并不总是同义的。已有调查表明，通用处方能够令各方满意，尤其是消费者的满意度（在丹麦的一项调查中，高达83%的患者对该安排表示满意）。此外，如果该系统运行良好，能立即节省开支（约7%）。然而，在大多数地方，该系统充其量只能在一半的情况下发挥作用，在美国最常见的情况是只有10%，在英国为36%。专业群体构成了最大的障碍。尤其是医生，对该系统的可取性表示极大怀疑。如果该系统要发挥作用，药理学家和医生必须有动力正确使用该系统。为了避免通用处方给药剂师和医生带来大量无报酬的额外工作，教育是必要的。丹麦卫生局必须保证市场上的同义词制剂实际上是同义的，这一点至关重要。最后，关于同义词制剂可配发程度的决定权必须掌握在负责处方的开方医生手中。
