Eaton D L
Med Res Eng. 1976;12(3):17-22.
Critical parameters involved in the selection of porous glass for use as support materials in the immobilization of biologically active materials are discussed. The importance of physical properties such as pore morphology, surface area and particle size relative to the final activity of the enzyme is shown using glucoamylase IME as a model system. The process of selection of specific materials with respect to the environmental conditions of the enzyme and the chemical durability of the support is considered, as are the mechanical properties required in the scale-up of an application.
讨论了在选择多孔玻璃作为固定生物活性材料的载体材料时涉及的关键参数。以糖化酶IME为模型系统，展示了诸如孔形态、表面积和粒径等物理性质相对于酶的最终活性的重要性。考虑了根据酶的环境条件和载体的化学耐久性选择特定材料的过程，以及应用放大所需的机械性能。
