Lapchinskaia I I
Vrach Delo. 1991 May(5):68-70.
It was found that patients with diabetic glomerulosclerosis showed an increased intensity of blood coagulation as well as essential diverse changes in the system of fibrinolysis. These changes were more pronounced in patients suffering of diabetes mellitus than in the diabetic patients without glomerulosclerosis. It is recommended to introduce into clinical practice the Lejen method with the purpose of determining indications to heparin therapy and dynamic control of patients during treatment with anticoagulants.
研究发现，糖尿病肾小球硬化患者的血液凝固强度增加，同时纤维蛋白溶解系统也发生了本质性的多样变化。这些变化在糖尿病患者中比在无肾小球硬化的糖尿病患者中更为明显。建议将勒珍方法引入临床实践，以确定肝素治疗的适应症，并在抗凝治疗期间对患者进行动态监测。
