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伦敦南部住院患者的种族与抗精神病药物处方质量

Ethnicity and quality of antipsychotic prescribing among in-patients in south London.

作者信息

Connolly Anne, Taylor David

机构信息

Pharmacy Department, Maudsley Hospital, Denmark Hill, London, UK.

出版信息

Br J Psychiatry. 2008 Aug;193(2):161-2. doi: 10.1192/bjp.bp.108.050427.

Abstract

Ethnicity may influence treatment decisions in mental disorders. We undertook a survey of the prescribing of antipsychotics for in-patients in three south London mental health trusts. A total of 255 patients (152 White, 103 Black) were included. Median dose of antipsychotic (% of licensed dose) was 58.3% for White and 50.0% for Black patients (adjusted effect size=0.14, 95% CI -0.34 to 0.63). High-dose antipsychotics were prescribed to 15.1% of White and 11.7% of Black patients (adjusted odds ratio (OR)=0.5, 95% CI 0.19-1.33), and antipsychotic polypharmacy was recorded for 25.7% and 31.1% respectively (adjusted OR=3.05, 95% CI 1.44-6.46). Prescribing quality was similar for Black and White patients.

摘要

种族可能会影响精神疾病的治疗决策。我们对伦敦南部三个精神卫生信托机构中住院患者的抗精神病药物处方情况进行了一项调查。总共纳入了255名患者(152名白人,103名黑人)。白人患者抗精神病药物的中位剂量(占许可剂量的百分比)为58.3%,黑人患者为50.0%(调整后的效应大小=0.14,95%置信区间为-0.34至0.63)。15.1%的白人患者和11.7%的黑人患者被开具了高剂量抗精神病药物(调整后的优势比(OR)=0.5,95%置信区间为0.19-1.33),抗精神病药物联合用药的记录分别为25.7%和31.1%(调整后的OR=3.05,95%置信区间为1.44-6.46)。黑人和白人患者的处方质量相似。

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